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author = "Carnielli, V.P."
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Found 4 documents, displaying page 1 of 1

Surfactant phosphatidylcholine half-life and pool size measurements in premature baboons developing bronchopulmonary dysplasia

Author(s) : Janssen, D.J. , Carnielli, V.P. , Cogo, P.E. , Seidner, S.R. , Luijendijk, I.H.I. , Wattimena, J.L. , Jobe, A.H. , Zimmermann, L.J.I.
Description : Because minimal information is available about surfactant metabolism in bronchopulmonary dysplasia, we measured half-lives and pool sizes of surfactant phosphatidylcholine in very preterm baboons recovering from respiratory distress syndrome and developing bronchopulmonary dysplasi...
Repository : RePub (Erasmus University Repository)
Language(s) : English

Endogenous surfactant turnover in preterm infants measured with stable isotopes

Author(s) : Bunt, J.E.H. , Zimmermann, L.J.I. , Wattimena, J.L. , Beek, R.H.Th. van , Sauer, P.J.J. , Carnielli, V.P.
Description : We studied surfactant synthesis and turnover in vivo in preterm infants using the stable isotope [U-13C]glucose, as a precursor for the synthesis of palmitic acid in surfactant phosphatidylcholine (PC). Six preterm infants (birth weight, 916 +/- 244 g; gestational age, ...
Repository : RePub (Erasmus University Repository)
Language(s) : English

Metabolism of endogenous surfactant in premature baboons and effect of prenatal corticosteroids

Author(s) : Bunt, J.E.H. , Carnielli, V.P. , Seidner, S.R. , Ikegami, M. , Darcos Wattimena, J.L. , Sauer, P.J.J. , Jobe, A.H. , Zimmermann, L.J.I.
Description : We studied the synthesis of surfactant and the effect of prenatal betamethasone treatment in vivo in very preterm baboons. Ten pregnant baboons were randomized to receive either betamethasone (beta) or saline (control) 48 and 24 h before preterm delivery. The newborn ba...
Repository : RePub (Erasmus University Repository)
Language(s) : English

The effect in premature infants of prenatal corticosteroids on endogenous surfactant synthesis as measured with stable isotopes

Author(s) : Bunt, J.E.H. , Carnielli, V.P. , Darcos Wattimena, J.L. , Hop, W.C.J. , Sauer, P.J.J. , Zimmermann, L.J.I.
Description : Most in vitro studies show that prenatal administration of corticosteroids stimulates the synthesis of surfactant phosphatidylcholine (PC), but studies in animals are controversial. Whether prenatal corticosteroids stimulate surfactant PC synthesis in humans has not bee...
Repository : RePub (Erasmus University Repository)
Language(s) : English
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Found 4 documents, displaying page 1 of 1