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author = "Bolund, Lars"
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Found 94 documents, displaying page 1 of 10

An improved PCR strategy for fast screening of specific and random integrations in rAAV-mediated gene targeted cell clones

Author(s) : Luo Yonglun , Bolund Lars , Sørensen Charlotte B
Description :

Abstract

Background

Gene targeting by homologous recombination using recombinant adeno-associated virus (rAAV) is becoming a useful tool for basic research and therapeutic applications due to the remarkably high targeting frequency of rAAV virus vectors. However, the screening for t...

Repository : DOAJ-Articles
Language(s) : English

An improved PCR strategy for fast screening of specific and random integrations in rAAV-mediated gene targeted cell clones

Author(s) : Luo, Yonglun , Bolund, Lars , Sørensen, Charlotte B
Description :
Repository : Europe PubMed Central
Language(s) : English

State of the art de novo assembly of human genomes from massively parallel sequencing data

Author(s) : Li Yingrui , Hu Yujie , Bolund Lars , Wang Jun
Description :

Abstract

Recent studies in human genomes have demonstrated the use of de novo assemblies to identify genetic variations that are difficult for mapping-based approaches. Construction of multiple human genome assemblies is enabled by massively parallel sequencing, but a conventional...

Repository : DOAJ-Articles
Language(s) : English

Estimation of tumor heterogeneity using CGH array data

Author(s) : Wang Kai , Li Jian , Li Shengting , Bolund Lars , Wiuf Carsten
Description :

Abstract

Background

Array-based comparative genomic hybridization (CGH) is a commonly-used approach to detect DNA copy number variation in whole genome-wide screens. Several statistical methods have been proposed to define genomic segments with different copy numbers in cancer tumor...

Repository : DOAJ-Articles
Language(s) : English

Estimation of tumor heterogeneity using CGH array data

Author(s) : Wang, Kai , Li, Jian , Li, Shengting , Bolund, Lars , Wiuf, Carsten
Description :
Repository : Europe PubMed Central
Language(s) : English

State of the art de novo assembly of human genomes from massively parallel sequencing data

Author(s) : Li, Yingrui , Hu, Yujie , Bolund, Lars , Wang, Jun
Description : Recent studies in human genomes have demonstrated the use of de novo assemblies to identify genetic variations that are difficult for mapping-based approaches. Construction of multiple human genome assemblies is enabled by massively parallel sequencing, but a conventional bioinformatics solution is ...
Repository : Europe PubMed Central
Language(s) : English

Tumor heterogeneity in neoplasms of breast, colon, and skin

Author(s) : Li Jian , Wang Kai , Jensen Thomas , Li Shengting , Bolund Lars , Wiuf Carsten
Description :

Abstract

Background

Different cell subpopulations in a single tumor may show diverse capacities for growth, differentiation, metastasis formation, and sensitivity to treatments. Thus, heterogeneity is an important feature of tumors. However, due to limitations in experimental and an...

Repository : DOAJ-Articles
Language(s) : English

Gene Expression Responses to FUS, EWS, and TAF15 Reduction and Stress Granule Sequestration Analyses Identifies FET-Protein Non-Redundant Functions

Author(s) : Blechingberg, Jenny , Luo, Yonglun , Bolund, Lars , Damgaard, Christian Kroun , Nielsen, Anders Lade
Description : The FET family of proteins is composed of FUS/TLS, EWS/EWSR1, and TAF15 and possesses RNA- and DNA-binding capacities. The FET-proteins are involved in transcriptional regulation and RNA processing, and FET-gene deregulation is associated with development of cancer and protein granule formations in ...
Repository : PURE Aarhus University
Language(s) : English

A three allele TaqI polymorphism at TOP1 gene

Author(s) : Sunde, Lone , Kjeldsen, Eigil , Andoh, Toshiwo , Keene, Jack D. , Bolund, Lars
Description :
Repository : Europe PubMed Central
Language(s) : English

Tumor heterogeneity in neoplasms of breast, colon, and skin

Author(s) : Li, Jian , Wang, Kai , Jensen, Thomas Dyrsø , Li, Shengting , Bolund, Lars , Wiuf, Carsten
Description :
Repository : Europe PubMed Central
Language(s) : English
1 2 3 4 5 > >>

Found 94 documents, displaying page 1 of 10