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author = "Bittencourt, Danielle"
1

Found 5 documents, displaying page 1 of 1

Cotranscriptional Splicing Potentiates the mRNA Production from a Subset of Estradiol-Stimulated Genes ▿

Author(s) : Bittencourt, Danielle , Dutertre, Martin , Sanchez, Gabriel , Barbier, Jérôme , Gratadou, Lise , Auboeuf, Didier
Description : While early steps of gene expression, such as transcription preinitiation, are known to often be rate limiting and to be regulated by such stimuli as steroid hormones, the potential impact of downstream steps, including splicing, on the mRNA production rate is unknown. In this work, we studied the e...
Repository : Europe PubMed Central
Language(s) : English

The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export

Author(s) : Zonta, Eleonora , Bittencourt, Danielle , Samaan, Samaan , Germann, Sophie , Dutertre, Martin , Auboeuf, Didier
Description : It is widely accepted that pre-mRNA maturation, including splicing, is tightly coupled to both transcription and mRNA export, but factors linking the three processes are less understood. By analysing the estrogen-regulated expression of the c-fos mRNA that is processed during transcription, we show ...
Repository : Europe PubMed Central
Language(s) : English

Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancer

Author(s) : Sanchez, Gabriel , Bittencourt, Danielle , Laud, Karine , Barbier, Jérôme , Delattre, Olivier , Auboeuf, Didier , Dutertre, Martin
Description : Pre-mRNA splicing and polyadenylation are tightly connected to transcription, and transcriptional stimuli and elongation dynamics can affect mRNA maturation. However, whether this regulatory mechanism has a physio/pathological impact is not known. In cancer, where splice variant expression is often ...
Repository : Europe PubMed Central
Language(s) : English

A Distinct Mechanism for Coactivator versus Corepressor Function by Histone Methyltransferase G9a in Transcriptional Regulation*

Author(s) : Purcell, Daniel J. , Jeong, Kwang Won , Bittencourt, Danielle , Gerke, Daniel S. , Stallcup, Michael R.
Description : Background: The transcriptional corepressor G9a also activates genes by an unknown mechanism.
Repository : Europe PubMed Central
Language(s) : English

Regulation of H-ras Splice Variant Expression by Cross Talk between the p53 and Nonsense-Mediated mRNA Decay Pathways▿ †

Author(s) : Barbier, Jérôme , Dutertre, Martin , Bittencourt, Danielle , Sanchez, Gabriel , Gratadou, Lise , de la Grange, Pierre
Description : When cells are exposed to a genotoxic stress, a DNA surveillance pathway that involves p53 is activated, allowing DNA repair. Eukaryotic cells have also evolved a mechanism called mRNA surveillance that controls the quality of mRNAs. Indeed, mutant mRNAs carrying premature translation termination co...
Repository : Europe PubMed Central
Language(s) : English
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Found 5 documents, displaying page 1 of 1