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author = "Bao, Jianjun"
1

Found 5 documents, displaying page 1 of 1

Loss of Cell Adhesion Causes Hydrocephalus in Nonmuscle Myosin II-B–ablated and Mutated Mice

Author(s) : Ma, Xuefei , Bao, Jianjun , Adelstein, Robert S.
Description : Ablation of nonmuscle myosin (NM) II-B in mice during embryonic development leads to marked enlargement of the cerebral ventricles and destruction of brain tissue, due to hydrocephalus. We have identified a transient mesh-like structure present at the apical border of cells lining the spinal canal o...
Repository : Europe PubMed Central
Language(s) : English

The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance

Author(s) : Pagel-Langenickel, Ines , Bao, Jianjun , Pang, Liyan , Sack, Michael N.
Description : Multiple organs contribute to the development of peripheral insulin resistance, with the major contributors being skeletal muscle, liver, and adipose tissue. Because insulin resistance usually precedes the development of type 2 diabetes mellitus (T2DM) by many years, understanding the pathophysiolog...
Repository : Europe PubMed Central
Language(s) : English

Role of the short isoform of myosin light chain kinase in the contraction of cultured smooth muscle cells as examined by its down-regulation

Author(s) : Bao, Jianjun , Oishi, Kazuhiko , Yamada, Tomohisa , Liu, Liqun , Nakamura, Akio , Uchida, Masaatsu K. , Kohama, Kazuhiro
Description : GbaSM-4 cells, smooth muscle cells derived from brain basilar artery, which express both 210-kDa long and 130-kDa short isoforms of myosin light chain kinase (MLCK), were infected with an adenovirus vector carrying a 1.4-kb catalytic portion of MLCK–cDNA in an antisense orientation. Western blot ana...
Repository : Europe PubMed Central
Language(s) : English

Controllable fabrication of PS/Ag core-shell-shaped nanostructures

Author(s) : Zhang, Chunjing , Zhu, Xianfang , Li, Haixia , Khan, Imran , Imran, Muhammad , Wang, Lianzhou , Bao, Jianjun , Cheng, Xuan
Description : In this paper, based on the previous steps, a facile in situ reduction method was developed to controllably prepare polystyrene/Ag (PS/Ag) core-shell-shaped nanostructures. The crucial procedure includes surface treatment of polystyrene core particles by cationic polyelectrolyte polyethyleneimine, i...
Repository : Europe PubMed Central
Language(s) : English

PGC-1α Integrates Insulin Signaling, Mitochondrial Regulation, and Bioenergetic Function in Skeletal Muscle*S⃞

Author(s) : Pagel-Langenickel, Ines , Bao, Jianjun , Joseph, Joshua J. , Schwartz, Daniel R. , Mantell, Benjamin S. , Xu, Xiuli
Description : The pathophysiology underlying mitochondrial dysfunction in insulin-resistant skeletal muscle is incompletely characterized. To further delineate this we investigated the interaction between insulin signaling, mitochondrial regulation, and function in C2C12 myotubes and in skeletal muscle. In my...
Repository : Europe PubMed Central
Language(s) : English
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Found 5 documents, displaying page 1 of 1