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author = "Aboobaker, A. Aziz"
1

Found 6 documents, displaying page 1 of 1

The TALE Class Homeobox Gene Smed-prep Defines the Anterior Compartment for Head Regeneration

Author(s) : Felix, Daniel A. , Aboobaker, A. Aziz
Description : Planaria continue to blossom as a model system for understanding all aspects of regeneration. They provide an opportunity to understand how the replacement of missing tissues from preexisting adult tissue is orchestrated at the molecular level. When amputated along any plane, planaria are capable of...
Repository : Europe PubMed Central
Language(s) : English

SMG-1 and mTORC1 Act Antagonistically to Regulate Response to Injury and Growth in Planarians

Author(s) : González-Estévez, Cristina , Felix, Daniel A. , Smith, Matthew D. , Paps, Jordi , Morley, Simon J. , James, Victoria
Description : Planarian flatworms are able to both regenerate their whole bodies and continuously adapt their size to nutrient status. Tight control of stem cell proliferation and differentiation during these processes is the key feature of planarian biology. Here we show that the planarian homolog of the phospho...
Repository : Europe PubMed Central
Language(s) : English

Combining Classical and Molecular Approaches Elaborates on the Complexity of Mechanisms Underpinning Anterior Regeneration

Author(s) : Evans, Deborah J. , Owlarn, Suthira , Tejada Romero, Belen , Chen, Chen , Aboobaker, A. Aziz
Description : The current model of planarian anterior regeneration evokes the establishment of low levels of Wnt signalling at anterior wounds, promoting anterior polarity and subsequent elaboration of anterior fate through the action of the TALE class homeodomain PREP. The classical observation that decapitation...
Repository : Europe PubMed Central
Language(s) : English

Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development

Author(s) : Aboobaker, A. Aziz , Tomancak, Pavel , Patel, Nipam , Rubin, Gerald M. , Lai, Eric C.
Description : MicroRNAs (miRNAs) are an extensive class of regulatory RNA whose specific functions in animals are generally unknown. Although computational methods have identified many potential targets of miRNAs, elucidating the spatial expression patterns of miRNAs is necessary to identify the sites of miRNA ac...
Repository : Europe PubMed Central
Language(s) : English

A Dual Platform Approach to Transcript Discovery for the Planarian Schmidtea Mediterranea to Establish RNAseq for Stem Cell and Regeneration Biology

Author(s) : Blythe, Martin J. , Kao, Damian , Malla, Sunir , Rowsell, Joanna , Wilson, Ray , Evans, Deborah , Jowett, Jamie , Hall, Amy
Description : The use of planarians as a model system is expanding and the mechanisms that control planarian regeneration are being elucidated. The planarian Schmidtea mediterranea in particular has become a species of choice. Currently the planarian research community has access to this whole genome sequencing p...
Repository : Europe PubMed Central
Language(s) : English

High Through-Put Sequencing of the Parhyale hawaiensis mRNAs and microRNAs to Aid Comparative Developmental Studies

Author(s) : Blythe, Martin J. , Malla, Sunir , Everall, Richard , Shih, Yu-huan , Lemay, Virginie , Moreton, Joanna , Wilson, Raymond
Description : Understanding the genetic and evolutionary basis of animal morphological diversity will require comparative developmental studies that use new model organisms. This necessitates development of tools for the study of genetics and also the generation of sequence information of the organism to be studi...
Repository : Europe PubMed Central
Language(s) : English
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Found 6 documents, displaying page 1 of 1