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author = "Aarts, J."

Found 122 documents, displaying page 9 of 13

Inhibition of NAD(P)H: quinone oxidoreductase by flavonoids in living cells

Description :
Repository : Wageningen University and Researchcenter Publications
Language(s) : English

In vivo relevance of two critical levels for NAD(P)H:quinone oxidoreductase (NQO1)-mediated cellular protection against electrophile toxicity found in vitro

Description : NAD(P)H:quinone oxidoreductase (NQO1)-mediated detoxification of quinones is suggested to be involved in cancer prevention. In the present study, using transfected CHO cells, it was demonstrated that the relation between NQO1 activity and the resulting protection against the cytotoxicity of menadion...
Repository : Wageningen University and Researchcenter Publications
Language(s) : English

Activation of EpRE-mediated gene transcription by quercetin glucuronides depends on their deconjugation

Description : Quercetin is a flavonoid reported to have health-promoting properties. Due to its extensive metabolism to glucuronides in vivo, questions were raised if studies conducted with quercetin aglycone, stating its health-promoting activity, are of actual relevance. Here we show that glucuronides of querce...
Repository : Wageningen University and Researchcenter Publications
Language(s) : English

Shifted concentration dependency of EpRE- and XRE-mediated gene expression points at monofunctional EpRE-mediated induction by flavonoids at physiologically relevant concentrations

Description : Flavonoids are important bioactive compounds, omnipresent in the human diet, and are reported to be bifunctional inducers. These phytochemicals are able to induce xenobiotic-responsive element (XRE)- and electrophile-responsive element (EpRE)-mediated gene expression, resulting in the induction of b...
Repository : Wageningen University and Researchcenter Publications
Language(s) : English

Proliferation assays for estrogenicity testing with high predictive value for the in vivo uterotrophic effect

Description : Proliferation assays based on human cell lines are the most used in vitro tests to determine estrogenic properties of compounds. Our objective was to characterise to what extent these in vitro tests provide alternatives for the in vivo Allen and Doisy test, a uterotrophic assay in immature or ovarie...
Repository : Wageningen University and Researchcenter Publications
Language(s) : English

The origin of high critical currents in YBa2Cu3O7-d thin films

Description :
Repository : DSpace at Vrije Universiteit Amsterdam
Language(s) : Undetermined

Charge Localization due to RKKY Interaction in the Spin Glass AuFe

Description : Measurements of electrodynamic response of of spin glass AuFe films in comparison with pure gold films are performed at frequencies from 0.3 THz (10 cm-1) up to 1000 THz (33000 cm-1) using different spectroscopic methods. At room temperatures the spectra of pure gold and of AuFe are typically meta...
Repository : arXiv
Language(s) : Undetermined

Found 122 documents, displaying page 9 of 13