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• (repositories = "Publikationer från Umeå Universitet" AND publisher = "Umeå : Kemi" AND subject = "peptidomimetic")
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repositories = "Publikationer från Umeå Universitet" > : "Umeå : Kemi" (x) > : "peptidomimetic" (x)
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Found 2 documents, displaying page 1 of 1

Peptidomimetics based on ring-fused 2-pyridones : probing pilicide function in uropathogenic E. coli and identification of Aβ-peptide aggregation inhibitors

Author(s) : Åberg, Veronica
Description : This thesis describes the synthesis and biological evaluation of highly substituted, ring-fused 2-pyridones. The utility of the bicyclic 2-pyridones to gain fundamental insights into the disease processes of bacterial infections and Alzheimer’s disease has been investigated. The 2-pyridones have mai...
Repository : Publikationer från Umeå Universitet
Language(s) : English

Synthesis and functionalization of ring-fused 2-pyridones : Targeting pili formation in E. coli

Author(s) : Pemberton, Nils
Description : Bicyclic dihydrothiazolo fused 2-pyridones have been studied as a new class of antibacterial agents, termed pilicides, that target the formation of adhesive bacterial surface organelles (pili) in pathogenic bacteria. Synthetic methods to further functionalize the bicyclic 2-pyridone scaffold have be...
Repository : Publikationer från Umeå Universitet
Language(s) : English
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Found 2 documents, displaying page 1 of 1