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author = "SCHEEN, André" > : "Insulin/secretion" (x)
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Found 7 documents, displaying page 1 of 1

Pathophysiology of insulin secretion.

Author(s) : Scheen, André
Description : Defects in pancreatic islet beta-cell function play a major role in the development of diabetes mellitus. Type 1 diabetes is caused by a more or less rapid destruction of pancreatic beta cells, and the autoimmune process begins years before the beta-cell destruction becomes complete, thereby providi...
Repository : ORBi (University of Liège)
Language(s) : English

Diabetes mellitus in the elderly: insulin resistance and/or impaired insulin secretion?

Author(s) : Scheen, André
Description : Elderly people are more glucose intolerant and insulin resistant than young individuals, and many of them will develop type 2 diabetes. It remains, however, controversial whether this decrease in function is due to an inevitable consequence of "biological aging" or due to environmental or lifestyle ...
Repository : ORBi (University of Liège)
Language(s) : English

Le glucagon-like peptide-1 (GLP-1), nouvelle cible dans le traitement du diabete de type 2. Glucagon-like peptide-1 (GLP-1), new target for the treatment of type 2 diabetes

Author(s) : Scheen, André
Description : Glucagon-like peptide-1 (GLP-1) is a gut hormone secreted in response to the ingestion of a meal. It exerts various favourable metabolic effects among which a glucose-dependent stimulation of insulin secretion, an inhibition of glucagon secretion, a slow down of gastric emptying, and a central anore...
Repository : ORBi (University of Liège)
Language(s) : French

L’hyperglycémie provoquée par voie orale (HGPO) revisitée 2e partie : Indices d’insulinosécrétion, d’insulinosensibilité et de disposition orale

Author(s) : SCHEEN, André , LUYCKX, Françoise
Description : L’hyperglycémie provoquée par voie orale (HGPO) est très utilisée pour diagnostiquer une diminution de la tolérance au glucose, un diabète sucré ou encore un diabète gestationnel. Les mesures concomitantes de l’insulinémie (éventuellement de peptide C) et de la glycémie permettent de dériver des ind...
Repository : ORBi (University of Liège)
Language(s) : French

Diabete sucre iatrogene: l'exemple des anti-psychotiques atypiques. [Drug-induced diabetes mellitus: the exemple of atypical antipsychotics]

Author(s) : Scheen, André , De Hert, M.
Description : As an example of iatrogenic diabetes, we discuss the problem of diabetes mellitus in patients receiving atypical antipsychotics. The risk of diabetes mellitus appears to be different according to various molecules with, by decreasing order, clozapine, olanzapine, risperidone and quetiapine, and fina...
Repository : ORBi (University of Liège)
Language(s) : French

Le medicament du mois. Sitagliptine (Januvia): incretinopotentiateur indique comme insulinosecretagogue dans le traitement du diabete de type 2. Sitagliptine (Januvia): incretin enhancer potentiating insulin secretion for the treatment of type 2 diabetes

Author(s) : Scheen, André , Van Gaal, L. F.
Description : Sitagliptin (Januvia) is the first selective antagonist of dipeptidylpeptidase-4, an enzyme that degrades glucagon-like peptide-1 (GLP-1). This hormone is mainly secreted by ileal L cells and this secretion is abnormally low in patients with type 2 diabetes. Sitagliptin increases post-meal insulin s...
Repository : ORBi (University of Liège)
Language(s) : French

Anticorps monoclonaux en diabétologie : jusqu’au bout du rêve ? Monoclonal antibodies in diabetes : almost approaching the dream ?

Author(s) : Philips, Jean-Christophe , Keymeulen, B. , Mathieu, C. , Scheen, André
Description : SUMMARY : Type 1 diabetes is characterized by the autoimmune- mediated destruction of the insulin-producing beta cells of the pancreatic islets of Langerhans. Several cells are potentially implicated in the selective destruction of beta cells, including the beta cells themselves, and T-lymphocytes a...
Repository : ORBi (University of Liège)
Language(s) : French
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Found 7 documents, displaying page 1 of 1