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author = "Paulino, C.D."
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Found 3 documents, displaying page 1 of 1

Modelos de interacção genética de dois genes em fenótipos

Author(s) : Sepúlveda, N , Paulino, C.D. , Penha-Gonçalves, C.
Description : Em trabalhos anteriores foram propostos diversos modelos estatísticos para a penetrância de forma a inferir a interacção de dois genes dial´elicos na construção de fenótipos binários complexos: modelos de acção independente, modelos de inibição e modelos de número mínimo de alelos. Estes modelos bas...
Repository : ARCA - Access to Research and Communication Annals
Language(s) : Portuguese

Bayesian analysis of allelic penetrance models for complex binary traits

Author(s) : Sepúlveda, N , Paulino, C.D. , Penha-Gonçalves, C.
Description : Complex binary traits result from an intricate network of genetic and environmental factors. To aid their genetic dissection, several generalized linear models have been described to detect interaction between genes. However, it is recognized that these models have limited genetic interpretation. To...
Repository : ARCA - Access to Research and Communication Annals
Language(s) : English

Allelic penetrance approach as a tool to model twolocus

Author(s) : Sepúlveda, N , Paulino, C.D , Carneiro, J , Penha-Gonçalves, C
Description : Many binary phenotypes do not follow a classical Mendelian inheritance pattern. Interaction between genetic and environmental factors is thought to contribute to the incomplete penetrance phenomena often observed in these complex binary traits. Several two-locus models for penetrance have been propo...
Repository : ARCA - Access to Research and Communication Annals
Language(s) : English
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Found 3 documents, displaying page 1 of 1