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author = "Karra, Daniela" > : "Research Article" (x)
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Nos2 Inactivation Promotes the Development of Medulloblastoma in Ptch1+/− Mice by Deregulation of Gap43–Dependent Granule Cell Precursor Migration

Author(s) : Haag, Daniel , Zipper, Petra , Westrich, Viola , Karra, Daniela , Pfleger, Karin , Toedt, Grischa , Blond, Frederik , Delhomme, Nicolas
Description : Medulloblastoma is the most common malignant brain tumor in children. A subset of medulloblastoma originates from granule cell precursors (GCPs) of the developing cerebellum and demonstrates aberrant hedgehog signaling, typically due to inactivating mutations in the receptor PTCH1, a pathomechanism ...
Repository : Europe PubMed Central
Language(s) : English
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