Results
author = "Jenkins, Andrew"
> : "English"
(x)
General Anesthetic Actions on GABAA Receptors
Description :
General anesthetic drugs interact with many receptors in the nervous system, but only a handful of these interactions are critical for producing anesthesia. Over the last 20 years, neuropharmacologists have revealed that one of the most important target sites for general anesthetics is the GABAA rec...
Repository :
Europe PubMed Central
Language(s) :
English
Discrete M3-M4 Intracellular Loop Subdomains Control Specific Aspects of γ-Aminobutyric Acid Type A Receptor Function*
Description :
The GABA type A receptor (GABAAR) is a member of the pentameric ligand gated ion channel (pLGIC) family that mediates ionotropic neurotransmission. Residues in the intracellular loop domain (ILD) have recently been shown to define part of the ion permeation pathway in several closely related members...
Repository :
Europe PubMed Central
Language(s) :
English
The Apparent Voltage Dependence of GABAA Receptor Activation and Modulation Is Inversely Related to Channel Open Probability
Description :
The GABA type A receptor (GABAAR) is expressed ubiquitously throughout the brain and is a target for many therapeutic agents, including general anesthetics and benzodiazepines, which enhance receptor function by increasing the open probability (Po) of the ion channel. It is commonplace for in vitro ...
Repository :
Europe PubMed Central
Language(s) :
English
Comparison of Norwegian poultry, waterborne and clinical isolates of Campylobacter jejuni by ribotyping
Author(s) :
Rosef, Olav
,
Paulauskas, Algimantas
,
Grude, Nils
,
Haslekås, Camilla
,
Jenkins, Andrew
Description :
Campylobacteriosis is the most frequently occurring food and waterborne gastroenteritis in Norway and 90% of cases are caused by Campylobacter jejuni. Campylobacteriosis is epidemiologically associated with use of non-disinfected water and consumption of contaminated poultry. In order to provide mol...
Repository :
NORA (Norwegian Open Research Archives)
Language(s) :
English
Comparison of Norwegian poultry, waterborne and clinical isolates of Campylobacter jejuni by ribotyping
Author(s) :
Rosef, Olav
,
Paulauskas, Algimantas
,
Grude, Nils
,
Haslekås, Camilla
,
Jenkins, Andrew
Description :
Campylobacteriosis is the most frequently occurring food and waterborne gastroenteritis in Norway and 90% of cases are caused by Campylobacter jejuni. Campylobacteriosis is epidemiologically associated with use of non-disinfected water and consumption of contaminated poultry. In order to provide mol...
Repository :
TEORA - Telemark Open Research Archive
Language(s) :
English
Inverse Effects on Gating and Modulation Caused by a Mutation in the M2-M3 Linker of the GABAA Receptor γ SubunitS⃞
Description :
M2-M3 linkers are receptor subunit domains known to be critical for the
normal function of cysteine-loop ligand-gated ion channels. Previous studies
of α and β subunits of type “A” GABA receptors suggest
that these linkers couple extracellular elements involved in GABA binding to
the transmembra...
Repository :
Europe PubMed Central
Language(s) :
English
A Residue in Loop 9 of the β2-Subunit Stabilizes the Closed State of the GABAA Receptor*
Description :
In γ-aminobutyric acid type A (GABAA) receptors, the structural elements that couple ligand binding to channel opening remain poorly defined. Here, site-directed mutagenesis was used to determine if Loop 9 on the non-GABA binding site interface of the β2-subunit may be involved in GABAA receptor act...
Repository :
Europe PubMed Central
Language(s) :
English
Which contacts of patients with meningococcal disease carry the pathogenic strain of Neisseria meningitidis? A population based study
Description :
Objectives: To determine the prevalence of the pathogenic strain of Neisseria meningitidis in contacts of patients with meningococcal disease, and to determine which contact groups are likely to be carriers and warrant chemoprophylaxis.
Repository :
Europe PubMed Central
Language(s) :
English
Clonal Distribution of Invasive Neisseria meningitidis Isolates from the Norwegian County of Telemark, 1987 to 1995
Description :
Forty-two Neisseria meningitidis isolates were obtained from patients with meningococcal disease in the Norwegian county of Telemark (January 1987 to March 1995), and all were compared by PCR amplicon restriction endonuclease analysis (PCR-AREA) of the dhps gene, chromosomal DNA fingerprinting, and ...
Repository :
Europe PubMed Central
Language(s) :
English
Borrelia burgdorferi sensu lato in Ixodes ricinus ticks from Norway: evaluation of a PCR test targeting the chromosomal flaB gene
Author(s) :
Jenkins, Andrew
,
Hvidsten, Dag
,
Matussek, Andreas
,
Lindgren, Per-Eric
,
Stuen, Snorre
,
Kristiansen, Bjørn-Erik
Description :
A consensus TaqMan real-time PCR test targeting the chromosomal flaB gene of Borrelia burgdorferi sensu lato was constructed. The test was compared with a recently published generic Light Upon eXtension (LUX) 16S rRNA real-time PCR test (Wilhelmsson et al. in J Clin Microbiol 48:4169–4176, 2010) on ...
Repository :
Europe PubMed Central
Language(s) :
English