Results
author = "FILLET, Georges"
> : "Transplantation, Homologous"
(x)
Erythropoiesis after nonmyeloablative stem-cell transplantation is not impaired by inadequate erythropoietin production as observed after conventional allogeneic transplantation.
Description :
BACKGROUND: It is now well established that after conventional allogeneic hematopoietic stem-cell transplantation (HSCT), erythropoietic recovery is impaired because erythropoietin (Epo) production remains inadequate for prolonged periods of time. However, erythropoietic reconstitution after nonmyel...
Repository :
ORBi (University of Liège)
Language(s) :
English
Immunotherapie du cancer par minigreffe de cellules souches hematopoietiques. Nonmyeloablative stem cell transplantation as cancer immunotherapy
Author(s) :
Willems, Evelyne
,
Baron, Frédéric
,
Vanstraelen, Gaëtan
,
Frere, Pascale
,
Fillet, Georges
,
Beguin, Yves
Description :
Allogeneic hematopoietic stem cell transplantation (HSCT) is used for the treatment of selected haematological malignancies. Its curative potential is based on two different mechanisms, i.e. the conditioning regimen and the graft-versus-host immunologic reactions. However, because of its toxicity, i...
Repository :
ORBi (University of Liège)
Language(s) :
French
Circulating erythropoietin levels after bone marrow transplantation: inappropriate response to anemia in allogeneic transplants.
Description :
We studied 24 recipients of autologous bone marrow transplantation (ABMT) or allogeneic BMT (BMT) to determine whether impaired erythropoietin (Epo) response to anemia could delay full erythropoietic recovery. Observed Epo levels were compared with predicted levels based on the relationship between ...
Repository :
ORBi (University of Liège)
Language(s) :
English
Treatment of leukemia relapse after allogeneic hematopoietic stem cell transplantation by donor lymphocyte infusion and STI-571.
Description :
Repository :
ORBi (University of Liège)
Language(s) :
English
Retrospective comparison of CD34-selected allogeneic peripheral blood stem cell transplantation followed by CD8-depleted donor lymphocyte infusions with unmanipulated bone marrow transplantation.
Description :
We have previously reported the feasibility of allogeneic CD34-selected PBSC transplantation followed by pre-emptive CD8-depleted DLI (study group). In this report, we retrospectively compare the clinical outcome of the 24 patients included in this study with an historical group of 35 patients recei...
Repository :
ORBi (University of Liège)
Language(s) :
English
Recombinant human erythropoietin therapy after allogeneic hematopoietic cell transplantation with a nonmyeloablative conditioning regimen: low donor chimerism predicts for poor response.
Author(s) :
Vanstraelen, Gaëtan
,
Baron, Frédéric
,
Willems, Evelyne
,
Bonnet, Christophe
,
Hafraoui, Kaoutar
,
Frere, Pascale
,
Fillet, Georges
Description :
PURPOSE: After allogeneic hematopoietic stem cell transplantation with nonmyeloablative conditioning (NMHCT), many patients experience prolonged anemia and require red blood cell (RBC) transfusions. We enrolled 60 consecutive patients undergoing NMHCT in a phase II trial to determine the optimal uti...
Repository :
ORBi (University of Liège)
Language(s) :
English
Optimization of recombinant human erythropoietin therapy after allogeneic hematopoietic stem cell transplantation.
Author(s) :
Baron, Frédéric
,
Sautois, Brieuc
,
Baudoux, Etienne
,
Matus, Geoffrey
,
Fillet, Georges
,
Beguin, Yves
Description :
OBJECTIVE: Allogeneic hematopoietic stem cell transplantation (HSCT) is associated with prolonged anemia caused by defective erythropoietin (Epo) production. We enrolled 34 recipients of an allogeneic HSCT in three consecutive trials to determine the optimal utilization of recombinant human erythrop...
Repository :
ORBi (University of Liège)
Language(s) :
English
Bacteremia after hematopoietic stem cell transplantation: incidence and predictive value of surveillance cultures.
Author(s) :
Frere, Pascale
,
Hermanne, J.-P.
,
Debouge, M.-H.
,
De Mol, Patrick
,
Fillet, Georges
,
Beguin, Yves
Description :
We studied 622 transplants undertaken between 1982 and 2001 to: (1) determine the incidence, timing and etiology of bacteremias, and (2) examine the ability of routine surveillance cultures to predict bacteremias. A total of 404 episodes (0.65 episode per patient) occurred in 248 patients, due to co...
Repository :
ORBi (University of Liège)
Language(s) :
English
Pre-emptive immunotherapy with CD8-depleted donor lymphocytes after CD34-selected allogeneic peripheral blood stem cell transplantation.
Author(s) :
Baron, Frédéric
,
Siquet, Jean
,
Schaaf-Lafontaine, Nicole
,
Baudoux, Etienne
,
Hermanne, Jean-Philippe
,
Fillet, Georges
Description :
BACKGROUND AND OBJECTIVES: To maximize graft-versus-leukemia (GVL) effects while minimizing the risk of graft-versus-host disease (GVHD), we undertook a study of allogeneic CD34-selected peripheral blood stem cell (PBSC) transplantation followed by CD8-depleted donor lymphocyte infusion (DLI). DESIG...
Repository :
ORBi (University of Liège)
Language(s) :
English
Infections after allogeneic hematopoietic stem cell transplantation with a nonmyeloablative conditioning regimen.
Author(s) :
Frere, Pascale
,
Baron, Frédéric
,
Bonnet, Christophe
,
Hafraoui, Kaoutar
,
Pereira-Martins, Maguy
,
Willems, Evelyne
Description :
Hematopoietic cell transplantation (HCT) following nonmyeloablative conditioning (NMSCT) may be associated with a reduced risk of infection compared to standard allogeneic HCT. We retrospectively analyzed incidence and risk factors of infection in 62 patients undergoing NMSCT with low-dose TBI +/- f...
Repository :
ORBi (University of Liège)
Language(s) :
English