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author = "BRESOLIN, NEREO" > : "Research Article" (x)

Found 14 documents, displaying page 1 of 2

Comparative analysis of the human dystrophin and utrophin gene structures.

Description : We present analysis of intronic sequences in the human DMD and UTRN genes. In both genes accumulation of repeated elements could account for intron expansion. Out-of-frame rod-domain exons have stronger splice sites and are separated by significantly longer introns as compared to in-frame exons. The...
Repository : Europe PubMed Central
Language(s) : English

Genome-Wide Identification of Susceptibility Alleles for Viral Infections through a Population Genetics Approach

Description : Viruses have exerted a constant and potent selective pressure on human genes throughout evolution. We utilized the marks left by selection on allele frequency to identify viral infection-associated allelic variants. Virus diversity (the number of different viruses in a geographic region) was used to...
Repository : Europe PubMed Central
Language(s) : English

Neural stem cell transplantation can ameliorate the phenotype of a mouse model of spinal muscular atrophy

Description : Spinal muscular atrophy (SMA), a motor neuron disease (MND) and one of the most common genetic causes of infant mortality, currently has no cure. Patients with SMA exhibit muscle weakness and hypotonia. Stem cell transplantation is a potential therapeutic strategy for SMA and other MNDs. In this stu...
Repository : Europe PubMed Central
Language(s) : English

Found 14 documents, displaying page 1 of 2