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repositories = "University of Oulu Repository - Jultika"
> : "wound healing"
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Found 7 documents, displaying page 1 of 1
Inflammatory response following abdominal surgery and its modulation by recombinant human granulocyte colony-stimulating factor (rhG-CSF, filgrastim)
Author(s) :
Wiik, Heikki
Description :
Abstract
The effects of perioperative filgrastim (rhG-CSF) and surgery per se on the postoperative acute phase reaction were studied by assessing leukocyte functions, cytokine levels and tenascin-C (Tn-C) and procollagen propeptide (PINP, PIIINP) concentrations in different body fluid compartments ...
Repository :
University of Oulu Repository - Jultika
Language(s) :
Undetermined
Collagenase-2 (matrix metalloproteinase-8) in tongue squamous cell carcinoma, bone osteosarcoma, and wound repair
Author(s) :
Korpi, Jarkko
Description :
Abstract
Degradation of extracellular matrix (ECM) and basement membrane (BM) are required both in normal physiological conditions such as wound healing and in pathological tissue remodelling such as chronic ulcers and cancers. Matrix metalloproteinases (MMPs) are an enzyme family, which can cleave...
Repository :
University of Oulu Repository - Jultika
Language(s) :
Undetermined
NF1 tumor suppressor in epidermal differentiation and growth - implications for wound epithelialization and psoriasis
Author(s) :
Koivunen, Jussi
Description :
Abstract
Neurofibromatosis type 1 (NF1) is a dominantly inherited neurocutaneous disorder caused by mutations in the NF1 gene. Common clinical manifestations associated with NF1 are neurofibromas, café-au-lait macules (CALM), axillary freckling and Lisch nodules of the iris. Other important manifes...
Repository :
University of Oulu Repository - Jultika
Language(s) :
Undetermined
The roles of collagen XVIII and its endostatin domain in wound healing, hair follicle cycling and bone development
Author(s) :
Seppinen, Lotta
Description :
Abstract
Collagen XVIII is a basement membrane proteoglycan, which has three variant N-termini. These variants are coded by two promoters; promoter 1 directs the synthesis of a short variant and promoter 2 directs the synthesis of two longer variants, of which the middle variant is generated from t...
Repository :
University of Oulu Repository - Jultika
Language(s) :
Undetermined
Insights into healing response in severe sepsis from a connective tissue perspective : a longitudinal case-control study on wound healing, collagen synthesis and degradation, and matrix metalloproteinases in patients with severe sepsis
Author(s) :
Gäddnäs, Fiia
Description :
Abstract
Sepsis is a major challenge for healing responses maintaining homeostasis. Coagulation and inflammation are activated at the whole-body level, even in undamaged tissues. Despite constantly growing knowledge and advances in care, high mortality in severe sepsis remains. It was hypothesised...
Repository :
University of Oulu Repository - Jultika
Language(s) :
Undetermined
NF1 tumor suppressor in skin : expression in response to tissue trauma and in cellular differentiation
Author(s) :
Ylä-Outinen, Heli
Description :
Abstract
Type 1 neurofibromatosis (NF1) syndrome is caused by a mutation of the NF1 gene. NF1 protein (neurofibromin) contains a domain which is related to the GTPase activating protein (GAP) and accelerates the switch of active Ras-GTP to inactive Ras-GDP. The clinical symptoms of NF1 patients inc...
Repository :
University of Oulu Repository - Jultika
Language(s) :
Undetermined
Collagen XVII and TIMP-1 in epithelial cell migration
Author(s) :
Parikka, Mataleena
Description :
Abstract
Collagen XVII (BP180) is a transmembrane component of hemidesmosomes, which connect basal keratinocytes to the basement membrane. The extracellular domain of collagen XVII is proteolytically shed from the cell surface and released to the extracellular matrix. Apart from its function in epi...
Repository :
University of Oulu Repository - Jultika
Language(s) :
Undetermined
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Found 7 documents, displaying page 1 of 1