Results
author = "Wu, Honglong"
1
Found 7 documents, displaying page 1 of 1
Genome-Wide DNA Methylation Changes between the Superficial and Deep Backfat Tissues of the Pig
Author(s) :
Li, Mingzhou
,
Wang, Tao
,
Wu, Honglong
,
Zhang, Jie
,
Zhou, Chaowei
,
Jiang, Anan
,
Li, Ruiqiang
,
Li, Xuewei
Description :
Adipose tissue is not only a storage organ involved in fuel metabolism, but also an endocrine organ involved in the regulation of insulin sensitivity, thermogenesis, immunity, and inflammation. There are anatomical, cellular, molecular and physiological differences among adipose tissues deposited in...
Repository :
Europe PubMed Central
Language(s) :
English
Double restriction-enzyme digestion improves the coverage and accuracy of genome-wide CpG methylation profiling by reduced representation bisulfite sequencing
Author(s) :
Wang Junwen
,
Xia Yudong
,
Li Lili
,
Gong Desheng
,
Yao Yu
,
Luo Huijuan
,
Lu Hanlin
,
Yi Na
,
Wu Honglong
,
Zhang Xiuqing
,
Tao Qian
Description :
Abstract
Background
Reduced representation bisulfite sequencing (RRBS) was developed to measure DNA methylation of high-CG regions at single base-pair resolution, and has been widely used because of its minimal DNA requirements and cost efficacy; however, the CpG coverage of genomic...
Repository :
DOAJ-Articles
Language(s) :
English
Co-methylated Genes in Different Adipose Depots of Pig are Associated with Metabolic, Inflammatory and Immune Processes
Author(s) :
Li, Mingzhou
,
Wu, Honglong
,
Wang, Tao
,
Xia, Yudong
,
Jin, Long
,
Jiang, Anan
,
Zhu, Li
,
Chen, Lei
,
Li, Ruiqiang
,
Li, Xuewei
Description :
It is well established that the metabolic risk factors of obesity and its comorbidities are more attributed to adipose tissue distribution rather than total adipose mass. Since emerging evidence suggests that epigenetic regulation plays an important role in the aetiology of obesity, we conducted a g...
Repository :
Europe PubMed Central
Language(s) :
English
Double restriction-enzyme digestion improves the coverage and accuracy of genome-wide CpG methylation profiling by reduced representation bisulfite sequencing
Author(s) :
Wang, Junwen
,
Xia, Yudong
,
Li, Lili
,
Gong, Desheng
,
Yao, Yu
,
Luo, Huijuan
,
Lu, Hanlin
,
Yi, Na
,
Wu, Honglong
,
Zhang, Xiuqing
Description :
Repository :
Europe PubMed Central
Language(s) :
English
The DNA Methylome of Human Peripheral Blood Mononuclear Cells
Author(s) :
Li, Yingrui
,
Zhu, Jingde
,
Tian, Geng
,
Li, Ning
,
Li, Qibin
,
Ye, Mingzhi
,
Zheng, Hancheng
,
Yu, Jian
,
Wu, Honglong
,
Sun, Jihua
Description :
Analysis across the genome of patterns of DNA methylation reveals a rich landscape of allele-specific epigenetic modification and consequent effects on allele-specific gene expression.
Repository :
Europe PubMed Central
Language(s) :
English
The DNA methylome of human peripheral blood mononuclear cells
Author(s) :
Li, Yingrui
,
Zhu, Jingde
,
Tian, Geng
,
Li, Ning
,
Li, Qibin
,
Ye, Mingzhi
,
Zheng, Hancheng
,
Yu, Jian
,
Wu, Honglong
,
Sun, Jihua
Description :
DNA methylation plays an important role in biological processes in human health and disease. Recent technological advances allow unbiased whole-genome DNA methylation (methylome) analysis to be carried out on human cells. Using whole-genome bisulfite sequencing at 24.7-fold coverage (12.3-fold per s...
Repository :
CURIS - University of Copenhagen
Language(s) :
English
Demographic history and rare allele sharing among human populations
Author(s) :
Gravel, Simon
,
Henn, Brenna M.
,
Gutenkunst, Ryan N.
,
Indap, Amit R.
,
Marth, Gabor T.
,
Clark, Andrew G.
,
Yu, Fuli
Description :
High-throughput sequencing technology enables population-level surveys of human genomic variation. Here, we examine the joint allele frequency distributions across continental human populations and present an approach for combining complementary aspects of whole-genome, low-coverage data and targete...
Repository :
Europe PubMed Central
Language(s) :
English
1
Found 7 documents, displaying page 1 of 1