Results
author = "Watanabe, Takashi"
Mechanism for Oxidation of High-Molecular-Weight Substrates by a Fungal Versatile Peroxidase, MnP2▿
Author(s) :
Tsukihara, Takahisa
,
Honda, Yoichi
,
Sakai, Ryota
,
Watanabe, Takahito
,
Watanabe, Takashi
Description :
Unlike general peroxidases, Pleurotus ostreatus MnP2 was reported to have a unique property of direct oxidization of high-molecular-weight compounds, such as Poly R-478 and RNase A. To elucidate the mechanism for oxidation of polymeric substrates by MnP2, a series of mutant enzymes were produced by ...
Repository :
Europe PubMed Central
Language(s) :
English
Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts
Description :
Several groups have attempted to develop gene therapy strategies to treat cancer via introduction of the wild-type (wt) p53 cDNA into cancer cells. Unfortunately, these approaches do not result in regulated expression of the p53 gene and do not reduce expression of the mutant p53 that is overexpress...
Repository :
Europe PubMed Central
Language(s) :
English
Cadherin-mediated Intercellular Adhesion and Signaling Cascades Involving Small GTPases
Description :
Epithelia form physical barriers that separate the internal milieu of the body from its external environment. The biogenesis of functional epithelia requires the precise coordination of many cellular processes. One of the key events in epithelial biogenesis is the establishment of cadherin-dependent...
Repository :
Europe PubMed Central
Language(s) :
English
Purification, Properties, and Cytotoxic Effect of a Bacteriocin from Mycobacterium smegmatis
Description :
The bacteriocin produced by Mycobacterium smegmatis ATCC 14468 was isolated, and a study was made of its chemical, physical, and biological properties. No appreciable bacteriocin activity was found in the culture supernatant fluids, but it was released in appreciable quantities after disruption of t...
Repository :
Europe PubMed Central
Language(s) :
English
Development of a closed-loop fes system using a 3-d magnetic position and orientation measurement system
Description :
We have developed a closed-loop FES system using a magnetic 3-D position and orientation measurement system (FASTRAK, Polhemus Inc). The purpose of this development was to resolve some experimental difficulties involved in our previous goniometer-based experimental system. The new system enabled us ...
Repository :
DOAJ-Articles
Language(s) :
English
Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced.
Author(s) :
Kamitani, Hideki
,
Taniura, Seijiro
,
Watanabe, Kenji
,
Sakamoto, Makoto
,
Watanabe, Takashi
,
Eling, Thomas
Description :
Histone deacetylase inhibitors that increase histone acetylation on transformed cells are being investigated as unique anticancer drugs. The aim of this investigation was to evaluate an antiproliferative activity of the histone deacetylase inhibitors sodium butyrate (NaBT) and trichostatin A on 5 gl...
Repository :
Europe PubMed Central
Language(s) :
English
Nonsteroidal Anti-inflammatory Drug-activated Gene (NAG-1/GDF15) Expression Is Increased by the Histone Deacetylase Inhibitor Trichostatin A*
Description :
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1) is a
putative tumor suppressor whose expression can be increased by drug treatment.
Glioblastoma is the most common central nervous system tumor, is associated
with high morbidity and mortality, and responds poorly to surgical, chemical,
...
Repository :
Europe PubMed Central
Language(s) :
English
Breeding of wastewater treatment yeasts that accumulate high concentrations of phosphorus
Author(s) :
Watanabe, Takashi
,
Ozaki, Noriatsu
,
Iwashita, Kazuhiro
,
Fujii, Tsutomu
,
Iefuji, Haruyuki
Description :
Inorganic phosphate is an essential nutrient. In general, microorganisms take up phosphorus when the extracellular phosphorus concentration is low, but not when it is high. In Saccharomyces cerevisiae, the major phosphate transporters, such as Pho84p, and acid phosphatases (APases), such as Pho5p, a...
Repository :
Europe PubMed Central
Language(s) :
English
threo-2-(2,6-Dimethoxyphenoxy)-1-(4-ethoxy-3-methoxyphenyl)propane-1,3-diol
Description :
In the crystal structure of the title compound, C20H26O7, a lignin model compound, the asymmetric unit contains two molecules which adopt almost identical overall conformations with some deviation in the region of the terminal hydroxyl groups. The two molecules are linked by an intermolecular O—H...
Repository :
Europe PubMed Central
Language(s) :
English
A Preliminary Test of Measurement of Joint Angles and Stride Length with Wireless Inertial Sensors for Wearable Gait Evaluation System
Description :
The purpose of this study is to develop wearable sensor system for gait evaluation using gyroscopes and accelerometers for application to rehabilitation, healthcare and so on. In this paper, simultaneous measurement of joint angles of lower limbs and stride length was tested with a prototype of wear...
Repository :
Europe PubMed Central
Language(s) :
English