Results
author = "Veldhuizen, E.J.A."
Identification of chicken cathelicidin-2 core elements involved in antibacterial and immunomodulatory activities
Author(s) :
Dijk, Albert van
,
Molhoek, E.M.
,
Veldhuizen, E.J.A.
,
Tjeerdsma-van Bokhoven, J.L.M.
,
Wagendorp, Eveline
,
Bikker, Floris
Description :
Chicken host defense peptide cathelicidin-2 (CATH-2) is known to exert antimicrobial and immunomodulatory
activities and consists of two -helices connected by a hinge region. Herewe report the biological
properties of the separate -helical segments and the importance of the proline residue in the ...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English
The carbohydrate recognition domain of collectins
Description :
Collectins are effector molecules of the innate immune system that play an
important role in the first line of defence against bacteria, viruses and
fungi. Most of their interactions with microorganisms are mediated
through their carbohydrate recognition domain (CRD), which binds in a
Ca2+-dependent...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English
Avian defensins
Description :
Modulation of defensin expression may be one way to improve animal health and to reduce zoonotic diseases. Defensins are small, cationic, and amphipathic cysteine-rich antibiotic peptides found in plants, insects, mammals and birds. Whereas α- and θ-defensins appear to be absent in birds, several β-...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English
Altered cutaneous expression of β-defensins in dogs with atopic dermatitis
Description :
Canine atopic dermatitis (AD) is a chronic allergic skin disorder with an immunopathogenesis comparable to that in humans with AD. The high frequency of recurrent infections with Staphylococcus pseudo intermedius and Malassezia pachydermatis may indicate a defective innate immune response in the ski...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English
Salmonella serovar specific upregulation of porcine defensins 1 and 2 in a jejunal epithelial cell line
Description :
Defensins are important antimicrobial effector peptides of the innate immune system,
which provides protection against bacterial infections in the intestine. Salmonella
Choleraesuis and Salmonella Typhimurium are the most commonly isolated serovars in
pig, but disease outcome is dependent on the Sal...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English
Phosphate analysis of natural sausage casings preserved in brines with phosphate additives as inactivating agent – Method validation
Description :
Certain phosphates have been identified as suitable additives for the improvement of the microbial and
mechanical properties of processed natural sausage casings. When mixed with NaCl (sodium chloride)
and used under specific treatment and storage conditions, these phosphates are found to prevent th...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English
Differential regulation of porcine β-defensins 1 and 2 upon Salmonella infection in the intestinal epithelial cell line IPI-2I
Author(s) :
Veldhuizen, E.J.A.
,
Hendriks, H.G.C.J.M.
,
Hogenkamp, A.
,
Gaastra, W.
,
Tooten, P.C.J.
,
Haagsman, H.P.
Description :
Intestinal epithelial cells represent the first line of defence against pathogenic bacteria in the lumen of the gut. Besides acting as a
physical barrier, epithelial cells orchestrate the immune response through the production of several innate immune mediator
molecules including β-defensins. Here, ...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
Dutch
Transcriptional expression levels of chicken collectins are effected by avian influenza A virus inoculation.
Author(s) :
Reemers, S.S.N.
,
Veldhuizen, E.J.A.
,
Fleming, C.
,
Haarlem, D.A. van
,
Haagsman, H.P.
,
Vervelde, L.
Description :
Mammalian collectins have been found to play an important role in the defense against influenza A virus H9N2 inoculation, but for chicken collectins this has not yet been clarified. The aim of this study was to determine the effect of avian influenza A virus (AIV) inoculation on collectin gene expre...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English
Recent advances in alveolar biology: Evolution and function of alveolar proteins
Author(s) :
Orgeig, S.
,
Hiemstra, P.S.
,
Veldhuizen, E.J.A.
,
Casals, C.
,
Clark, H.W.
,
Hackzu, A.
,
Knudsen, L.
,
Possmayer, F.
Description :
This review is focused on the evolution and function of alveolar proteins. The lung faces physical and
environmental challenges, due to changing pressures/volumes and foreign pathogens, respectively. The
pulmonary surfactant system is integral in protecting the lung from these challenges via two gro...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English
A cathelicidin-2-derived peptide effectively impairs Staphylococcus epidermidis biofilms
Description :
Staphylococcus epidermidis is a major cause of nosocomial infections owing to its ability to form biofilms
on the surface of medical devices. Biofilms are surface-adhered bacterial communities. In mature biofilms
these communities are encased in an extracellular matrix composed of bacterial polysacc...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English