Results
author = "Quertemont, Etienne"
Alcoolisme ou aldehydisme : Role de l'acetaldehyde dans les effets psychotropes de l'alcool Alcoholism or acetaldehydism: role of acetaldehyde in the psychotropic effects of alcohol
Author(s) :
Quertemont, Etienne
Description :
De récentes études ont suggéré que l’acétaldéhyde, premier produit du métabolisme de l’éthanol, participe aux effets psychotropes résultant de la consommation d’alcool. L’acétaldéhyde semble particulièrement impliqué dans les effets renforçants de l’éthanol, ce qui suggère un rôle important pour ce ...
Repository :
ORBi (University of Liège)
Language(s) :
French
Effet placebo, effet nocebo: comment la science explique les guérions miraculeuses
Author(s) :
Quertemont, Etienne
Description :
L’effet placebo est habituellement considéré comme l’ensemble des réponses psychologiques et physiologiques des patients à une substance inerte. On parle d’effet placebo lorsque cette réponse constitue un effet bénéfique pour la santé et d’effet nocebo lorsque les conséquences sont néfastes. Cependa...
Repository :
ORBi (University of Liège)
Language(s) :
French
Animal models of drug addiction: advantages and limitations
Author(s) :
Quertemont, Etienne
Description :
Various animal models have been developed to investigate the neurobiological and behavioral mechanisms of drug addiction. The most popular of these animal models include the locomotor sensitization paradigm, the place conditioning procedure and the self-administration technique. With these technique...
Repository :
ORBi (University of Liège)
Language(s) :
English
Neurobiological and genetic aspects of alcohol addiction: a special focus on acetaldehyde, the first metabolite of ethanol
Author(s) :
Quertemont, Etienne
Description :
Although alcoholism is one of the most common forms of addiction, its neurobiological mechanisms still remain unclear. The reinforcing properties of ethanol are mediated by the interaction of multiple neurotransmitter systems, including dopamine, serotonin, glutamate, GABA, endogenous opioids and en...
Repository :
ORBi (University of Liège)
Language(s) :
English
Acetaldehyde and the central effects of alcohol: Beyond the discrepancies between animal and human studies
Author(s) :
Quertemont, Etienne
Description :
Whereas human studies keep reporting evidence that acetaldehyde accumulation prevents alcohol drinking and alcoholism, animal studies support a rewarding rather than aversive role for acetaldehyde. In recent years, the reinforcing properties of acetaldehyde were demonstrated in various rodent strain...
Repository :
ORBi (University of Liège)
Language(s) :
English
How to Statistically Show the Absence of an Effect Comment démontrer statistiquement l'absence d'un effet
Author(s) :
Quertemont, Etienne
Description :
In experimental studies, the lack of statistical significance is often interpreted as the absence of an effect. Unfortunately, such a conclusion is often a serious misinterpretation. Indeed, non-significant results are just as often the consequence of an insufficient statistical power. In order to c...
Repository :
ORBi (University of Liège)
Language(s) :
English
Ethanol-conditioned withdrawal syndrome
Description :
The withdrawal syndrome is closely related to the concepts of tolerance and physical dependence. The chronic consumption of a drug is believed to induce adaptive changes that are designed to oppose the acute effects of the drug. Such adaptive changes increase the tolerance to acute drug effects but ...
Repository :
ORBi (University of Liège)
Language(s) :
English
Effets comportementaux et neurochimiques de stimuli associés à l’administration d'éthanol: implications pour les comportements d'alcoolisation Behavioral and neurochemical effects of ethanol-conditioned stimuli: implications in alcohol consumption
Description :
Les drogues, y compris l’alcool, peuvent servir de stimuli inconditionnels dans des situations d’apprentissage par conditionnement. Les stimuli environnementaux qui accompagnent systématiquement l’administration d’alcool peuvent ainsi acquérir le statut de stimuli conditionnés capables d’induire à e...
Repository :
ORBi (University of Liège)
Language(s) :
French
Characterization of the development of a behavioural sensitization in female Swiss mice
Description :
Repository :
ORBi (University of Liège)
Language(s) :
English
Role of acetaldehyde in mediating the pharmacological and behavioral effects of alcohol
Description :
Acetaldehyde is the first active breakdown product (i.e., metabolite) generated during alcohol metabolism. It has toxic properties but also exerts other actions on the body (i.e., has pharmacological properties). Recent studies have shown that the direct administration of acetaldehyde, especially in...
Repository :
ORBi (University of Liège)
Language(s) :
English