Results
author = "Passweg, Jakob R."
Immunosuppressive treatment for aplastic anemia: are we hitting the ceiling?
Description :
The combination of antithymocyte globulin of horse origin and cyclosporine A is the standard treatment for aplastic anemia in patients not eligible for bone marrow transplantation. In this perspective article, Drs. Passweg and Tichelli discuss the current immunosuppressive therapy of aplastic anemia...
Repository :
Europe PubMed Central
Language(s) :
English
Towards rational graft-versus-host disease prophylaxis
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Improved outcome of patients older than 30 years receiving HLA-identical sibling hematopoietic stem cell transplantation for severe acquired aplastic anemia using fludarabine-based conditioning: a comparison with conventional conditioning regimen
Author(s) :
Maury, Sébastien
,
Bacigalupo, Andrea
,
Anderlini, Paolo
,
Aljurf, Mahmoud
,
Marsh, Judith
,
Socié, Gérard
,
Oneto, Rosi
Description :
Upfront or second line allogeneic hematopoietic stem cell transplantation (HSCT) offers a good disease-free survival option for patients suffering from severe idiopathic aplastic anemia. This report shows improved outcome of reduced-intensity versus conventional conditioning in HLA-identical sibling...
Repository :
Europe PubMed Central
Language(s) :
English
Prevention of pure red cell aplasia after major or bidirectional ABO blood group incompatible hematopoietic stem cell transplantation by pretransplant reduction of host anti-donor isoagglutinins
Author(s) :
Stussi, Georg
,
Halter, Jörg
,
Bucheli, Eveline
,
Valli, Piero V.
,
Seebach, Lutz
,
Gmür, Jürg
,
Gratwohl, Alois
,
Schanz, Urs
Description :
In this study of a large group of patients who underwent major ABO incompatible hematopoietic stem cell transplantation, it was found that pre-transplant reduction of anti-donor isoagglutinins prevented post-transplant pure red cell aplasia.
Repository :
Europe PubMed Central
Language(s) :
English
Bone marrow transplantation for severe aplastic anemia: a randomized controlled study of conditioning regimens
Author(s) :
Champlin, Richard E.
,
Perez, Waleska S.
,
Passweg, Jakob R.
,
Klein, John P.
,
Camitta, Bruce M.
,
Gluckman, Eliane
Description :
The addition of antithymocyte globulin (ATG) to a regimen of high-dose cyclophosphamide has been advocated to enhance engraftment after allogeneic bone marrow transplantation (BMT) for severe aplastic anemia (SAA). In a prospective clinical trial, 134 patients were randomly assigned to receive cyclo...
Repository :
Europe PubMed Central
Language(s) :
English
Persistence of recipient-type endothelium after allogeneic hematopoietic stem cell transplantation
Author(s) :
Mueller, Regula J.
,
Stussi, Georg
,
Puga Yung, Gisella
,
Nikolic, Milica
,
Soldini, Davide
,
Halter, Jörg
,
Meyer-Monard, Sandrine
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Impact of age on outcomes after bone marrow transplantation for acquired aplastic anemia using HLA-matched sibling donors
Author(s) :
Gupta, Vikas
,
Eapen, Mary
,
Brazauskas, Ruta
,
Carreras, Jeanette
,
Aljurf, Mahmoud
,
Gale, Robert Peter
,
Hale, Gregory A.
Description :
Repository :
Europe PubMed Central
Language(s) :
English
IL-2 Stimulated but Not Unstimulated NK Cells Induce Selective Disappearance of Peripheral Blood Cells: Concomitant Results to a Phase I/II Study
Author(s) :
Brehm, Claudia
,
Huenecke, Sabine
,
Quaiser, Andrea
,
Esser, Ruth
,
Bremm, Melanie
,
Kloess, Stephan
,
Soerensen, Jan
,
Kreyenberg, Hermann
Description :
In an ongoing clinical phase I/II study, 16 pediatric patients suffering from high risk leukemia/tumors received highly purified donor natural killer (NK) cell immunotherapy (NK-DLI) at day (+3) +40 and +100 post haploidentical stem cell transplantation. However, literature about the influence of NK...
Repository :
Europe PubMed Central
Language(s) :
English
Bone marrow versus peripheral blood as the stem cell source for sibling transplants in acquired aplastic anemia: survival advantage for bone marrow in all age groups
Author(s) :
Bacigalupo, Andrea
,
Socié, Gérard
,
Schrezenmeier, Hubert
,
Tichelli, Andre
,
Locasciulli, Anna
,
Fuehrer, Monika
,
Risitano, Antonio M.
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Effect of stem cell source on outcomes after unrelated donor transplantation in severe aplastic anemia
Author(s) :
Eapen, Mary
,
Le Rademacher, Jennifer
,
Antin, Joseph H.
,
Champlin, Richard E.
,
Carreras, Jeanette
,
Fay, Joseph
,
Passweg, Jakob R.
Description :
Outcome after unrelated donor bone marrow (BM) transplantation for severe aplastic anemia (SAA) has improved, with survival rates now approximately 75%. Increasing use of peripheral blood stem and progenitor cells (PBPCs) instead of BM as a graft source prompted us to compare outcomes of PBPC and BM...
Repository :
Europe PubMed Central
Language(s) :
English