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author = "Pacheco-Figueiredo, Luís"
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TP53 codon 72 polymorphism in susceptibility, overall survival, and adjuvant therapy response of gliomas
Author(s) :
Lima-Ramos, Vítor
,
Pacheco-Figueiredo, Luís
,
Costa, Sandra Maria Araújo da
,
Pardal, Fernando
,
Silva, Ana
,
Amorim, Júlia
Description :
TP53 is a key tumor suppressor gene that encodes a transcriptional factor involved in several cellular mechanisms, including growth arrest, DNA repair, and induction of apoptosis. In addition to TP53 gene mutations, a common polymorphism, Arg72Pro, has been involved in the carcinogenesis process. Th...
Repository :
RepositóriUM - University of Minho Institutional Repository
Language(s) :
English
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