Results
author = "Lison, Dominique"
Relative contributions of affinity and intrinsic efficacy to aryl hydrocarbon receptor ligand potency
Author(s) :
Lison, Dominique
Description :
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Importance of biotransformation pathways for interpreting biological monitoring of exposure.
Author(s) :
Lison, Dominique
Description :
A detailed characterisation of the biotransformation pathways followed by the chemical of interest is, evidently, of primordial importance to design reliable biomonitoring programs. This short overview discusses some recent studies that are of potential interest for the development of new avenues of...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Mercapturic acids revisited as biomarkers of exposure to reactive chemicals in occupational toxicology: a minireview.
Description :
A minireview is presented concerning the use of mercapturic acids as biological exposure index for electrophilic chemicals. Besides pure analytical aspects, this minireview considers possible issues in relation to (a) the added value of mercapturic acids as compared to other well validated biomarker...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Evaluation of the role of reactive oxygen species in the interactive toxicity of carbide-cobalt mixtures on macrophages in culture.
Description :
The lung toxicity of a carbide-cobalt mixture is more important than that of each individual component; the mechanism of this interaction is not understood. The capacity of cobalt metal particles alone and mixed with different carbides to generate hydroxyl radicals was examined with the deoxyribose ...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Urinary cotinine as a tobacco-smoke exposure index: a minireview.
Description :
A minireview is presented concerning the use of cotinine as a tobacco-smoke exposure index. First, general considerations about methods for the determination of urinary cotinine are presented. Besides pure analytical aspects, this minireview considers major problems encountered in the establishment ...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Liver abnormalities and hydrochlorofluorocarbons - Reply
Description :
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
The Interaction of Cobalt Metal With Different Carbides and Other Mineral Particles On Mouse Peritoneal-macrophages
Description :
Chronic inhalation of hard metal particles can produce an interstitial lung disease (hard metal disease). Recent studies on rats and on isolated alveolar and peritoneal macrophages have demonstrated that this disorder can be explained by an interaction between cobalt metal (Co) and tungsten carbide ...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Effects of Sulfur Mustard On Selected Biochemical Parameters of Murine Peritoneal-macrophages in Culture
Description :
The effect of the vesicating agent sulfur mustard (SM) has been investigated in vitro using murine peritoneal macrophages. The rationale for this study was three-fold: (1) the first symptoms after exposure to SM are mucous and cutaneous erythema, itching and oedema suggesting that inflammatory cells...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Effect of retinoic acid on asbestos induced plasminogen activator activity of peritoneal macrophages.
Description :
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English
Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism.
Description :
The involvement of cytochrome P450 2E1 (CYP2E1) in the metabolism of N-methyl-2-pyrrolidone (NMP) was studied with three experimental approaches: in the rat, in vitro in human microsomes, and in human volunteers. NMP was administered dermally (40 mg/kg) to OFA rats to examine the influence of CYP2E1...
Repository :
DIAL - Dépôt Institutionnel de l'Académie Louvain
Language(s) :
English