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author = "Kahn, Ari B"
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Found 7 documents, displaying page 1 of 1

SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

Description :

Abstract

Background

Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant challenges for contemporary biological assays. For example, RT-PCR validation of gene expression mic...

Repository : DOAJ-Articles
Language(s) : English

SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis

Description :

Abstract

Background

There are many fewer genes in the human genome than there are expressed transcripts. Alternative splicing is the reason. Alternatively spliced transcripts are often specific to tissue type, developmental stage, environmental condition, or disease state. Accurate ...

Repository : DOAJ-Articles
Language(s) : English

Ontogenomic study of the relationship between number of gene splice variants and GO categorization

Description : Motivation: Splice variation plays important roles in evolution and cancer. Different splice variants of a gene may be characteristic of particular cellular processes, subcellular locations or organs. Although several genomic projects have identified splice variants, there have been no large-scale c...
Repository : Europe PubMed Central
Language(s) : English

RedundancyMiner: De-replication of redundant GO categories in microarray and proteomics analysis

Description :

Abstract

Background

The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. Tools such as GoMiner can leverage GO to perform ontological analysis of microarray and proteomics studies...

Repository : DOAJ-Articles
Language(s) : English
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Found 7 documents, displaying page 1 of 1