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author = "Hofhaus, G"
1
Found 5 documents, displaying page 1 of 1
Efficient selection and characterization of mutants of a human cell line which are defective in mitochondrial DNA-encoded subunits of respiratory NADH dehydrogenase.
Description :
The mitochondrial NADH dehydrogenase (complex I) in mammalian cells is a multimeric enzyme consisting of approximately 40 subunits, 7 of which are encoded in mitochondrial DNA (mtDNA). Very little is known about the function of these mtDNA-encoded subunits. In this paper, we describe the efficient i...
Repository :
Europe PubMed Central
Language(s) :
English
Lack of assembly of mitochondrial DNA-encoded subunits of respiratory NADH dehydrogenase and loss of enzyme activity in a human cell mutant lacking the mitochondrial ND4 gene product.
Description :
In most eukaryotic cells, the respiratory chain NADH dehydrogenase (Complex I) is a multimeric enzyme under dual (nuclear and mitochondrial) genetic control. Several genes encoding subunits of this enzyme have been identified in the mitochondrial genome from various organisms, but the functions of t...
Repository :
Europe PubMed Central
Language(s) :
English
MtDNA mutations associated with sideroblastic anaemia cause a defect of mitochondrial cytochrome c oxidase
Description :
Repository :
UCL Eprints
Language(s) :
Undetermined
Comprehensive, rapid and sensitive detection of sequence variants of human mitochondrial tRNA genes.
Description :
In the present study, a comprehensive, rapid and sensitive method for screening sequence variation of the human mitochondrial tRNA genes has been developed. For this purpose, the denaturing gradient gel electrophoresis (DGGE) technique has been appropriately modified for simultaneous mutation analys...
Repository :
Europe PubMed Central
Language(s) :
English
Identification and electron microscopic analysis of a chaperonin oligomer from Neurospora crassa mitochondria.
Description :
A 7-fold symmetric particle has been identified in Neurospora crassa which is most probably the mitochondrial chaperonin. The particle, about 12 nm in diameter, appears in preparations of cytochrome reductase, and is shown to contain a 60 kd protein which cross-reacts with anti-GroEL antibodies. Res...
Repository :
Europe PubMed Central
Language(s) :
English
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Found 5 documents, displaying page 1 of 1