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author = "Freyer, Jennifer"
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Found 7 documents, displaying page 1 of 1
Regulation und funktionelle Rolle des murinen Transkriptionsfaktors Foxp3 in T-Zellen
Author(s) :
Freyer, Jennifer Sandra Silvia
Description :
In dieser Arbeit wurde die funktionelle Rolle und Regulation des murinen Transkriptionsfaktor Foxp3 untersucht. Der erste wesentliche Teil zur Analyse der funktionellen Rolle war dabei die Erzeugung einer BAC- transgenen Maus. Hierfür wurde ein Zielgenvektor mit der kodierenden Region des eYFPs und ...
Repository :
Humboldt University of Berlin, GERMANY, Document Server
Language(s) :
German
Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
Author(s) :
Lahl, Katharina
,
Loddenkemper, Christoph
,
Drouin, Cathy
,
Freyer, Jennifer
,
Arnason, Jon
,
Eberl, Gérard
,
Hamann, Alf
Description :
The scurfy mutant mouse strain suffers from a fatal lymphoproliferative disease leading to early death within 3–4 wk of age. A frame-shift mutation of the forkhead box transcription factor Foxp3 has been identified as the molecular cause of this multiorgan autoimmune disease. Foxp3 is a central cont...
Repository :
Europe PubMed Central
Language(s) :
English
Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease.
Author(s) :
Lahl, Katharina
,
Loddenkemper, Christoph
,
Drouin, Cathy
,
Freyer, Jennifer
,
Arnason, Jon
,
Eberl, Gérard
,
Hamann, Alf
Description :
The scurfy mutant mouse strain suffers from a fatal lymphoproliferative disease leading to early death within 3-4 wk of age. A frame-shift mutation of the forkhead box transcription factor Foxp3 has been identified as the molecular cause of this multiorgan autoimmune disease. Foxp3 is a central cont...
Repository :
HAL - Hyper Article on Line
Language(s) :
English
Replacement of connexin43 by connexin26 in transgenic mice leads to dysfunctional reproductive organs and slowed ventricular conduction in the heart
Author(s) :
Winterhager Elke
,
Pielensticker Nicole
,
Freyer Jennifer
,
Ghanem Alexander
,
Schrickel Jan W
,
Kim Jung-Sun
,
Behr Rüdiger
Description :
Abstract
Background
In order to further distinguish unique from general functions of connexin43, we have generated mice in which the coding region of connexin43 was replaced by that of connexin26.
Results
Heterozygous mothers showed impaired mammary gland development r...
Repository :
DOAJ-Articles
Language(s) :
English
Replacement of connexin43 by connexin26 in transgenic mice leads to dysfunctional reproductive organs and slowed ventricular conduction in the heart; Research article
Author(s) :
Winterhager, Elke
,
Pielensticker, Nicole
,
Freyer, Jennifer
,
Ghanem, Alexander
,
Schrickel, Jan W.
,
Kim, Jung-Sun
Description :
Background: In order to further distinguish unique from general functions of connexin43, we have generated mice in which the coding region of connexin43 was replaced by that of connexin26.Results: Heterozygous mothers showed impaired mammary gland development responsible for decreased lactation and ...
Repository :
GoeScholar (Publikationenserver der Georg-August-Universität Göttingen)
Language(s) :
English
Replacement of connexin43 by connexin26 in transgenic mice leads to dysfunctional reproductive organs and slowed ventricular conduction in the heart
Author(s) :
Winterhager, Elke
,
Pielensticker, Nicole
,
Freyer, Jennifer
,
Ghanem, Alexander
,
Schrickel, Jan W
,
Kim, Jung-Sun
Description :
Repository :
Europe PubMed Central
Language(s) :
English
Epigenetic Control of the foxp3 Locus in Regulatory T Cells
Author(s) :
Floess, Stefan
,
Freyer, Jennifer
,
Siewert, Christiane
,
Baron, Udo
,
Olek, Sven
,
Polansky, Julia
,
Schlawe, Kerstin
Description :
Compelling evidence suggests that the transcription factor Foxp3 acts as a master switch governing the development and function of CD4+ regulatory T cells (Tregs). However, whether transcriptional control of Foxp3 expression itself contributes to the development of a stable Treg lineage has thus far...
Repository :
Europe PubMed Central
Language(s) :
English
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Found 7 documents, displaying page 1 of 1