Results
author = "Curk, Tomaž"
Computational approaches for gene network discovery
Author(s) :
Curk, Tomaž
Description :
This dissertation proposes a set of computational methods for inference of gene networks from heterogeneous data sources. These methods address problems of function prediction using different computational phenotypes, methods for the analysis of gene regulatory regions, and methods for decomposition...
Repository :
ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) :
Undetermined
SNPsyn: detection and exploration of SNP-SNP interactions
Description :
SNPsyn (http://snpsyn.biolab.si) is an interactive software tool for the discovery of synergistic pairs of single nucleotide polymorphisms (SNPs) from large genome-wide case-control association studies (GWAS) data on complex diseases. Synergy among SNPs is estimated using an information-theoretic ap...
Repository :
ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) :
Undetermined
SNPsyn: detection and exploration of SNP–SNP interactions
Description :
SNPsyn (http://snpsyn.biolab.si) is an interactive software tool for the discovery of synergistic pairs of single nucleotide polymorphisms (SNPs) from large genome-wide case-control association studies (GWAS) data on complex diseases. Synergy among SNPs is estimated using an information-theoretic ap...
Repository :
Europe PubMed Central
Language(s) :
English
Does replication groups scoring reduce false positive rate in SNP interaction discovery?
Description :
Abstract
Background
Computational methods that infer single nucleotide polymorphism (SNP) interactions from phenotype data may uncover new biological mechanisms in non-Mendelian diseases. However, practical aspects of such analysis face many problems. Present experimental studies ty...
Repository :
DOAJ-Articles
Language(s) :
English
Does replication groups scoring reduce false positive rate in SNP interaction discovery?
Description :
BACKGROUNG. Computational methods that infer single nucleotide polymorphism (SNP) interactions from phenotype data may uncover new biological mechanisms in non-Mendelian diseases. However, practical aspects of such analysis face many problems. Present experimental studies typically use SNP arrays wi...
Repository :
ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) :
Undetermined
Inference of the Molecular Mechanism of Action from Genetic Interaction and Gene Expression Data
Description :
Inference of new and useful hypotheses from heterogeneous sources of genome-scale experimental data requires new computational methods that can integrate different types of data. Gene expression and genetic interaction data are two most informative data types, each allowing the identification of gen...
Repository :
ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) :
Undetermined
VizRank: Finding Informative Data Projections in Functional Genomics by Machine Learning
Description :
VizRank is a tool that finds interesting two-dimensional projections of class-labeled data. When applied to multi-dimensional functional genomics data sets, VizRank can systematically find relevant biological patterns.
Repository :
ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) :
Undetermined
Rule-based clustering for gene promoter structure discovery
Description :
BACKGROUND: The genetic cellular response to internal and external changes is determined by the sequence and structure of gene-regulatory promoter regions. OBJECTIVES: Using data on gene-regulatory elements (i.e., either putative or known transcription factor binding sites) and data on gene expressi...
Repository :
ePrints.FRI - Fakulteta za računalništvo in informatiko, Univerza v Ljubljani
Language(s) :
Undetermined
Does replication groups scoring reduce false positive rate in SNP interaction discovery?
Description :
Repository :
Europe PubMed Central
Language(s) :
English
dictyExpress: a Dictyostelium discoideum gene expression database with an explorative data analysis web-based interface
Description :
Abstract
Background
Bioinformatics often leverages on recent advancements in computer science to support biologists in their scientific discovery process. Such efforts include the development of easy-to-use web interfaces to biomedical databases. Recent advancements in interactive w...
Repository :
DOAJ-Articles
Language(s) :
English