Results
author = "Boven, L.A."
1
Found 5 documents, displaying page 1 of 1
A single mutation within the V3 envelope neutralization domain of feline immunodeficiency virus determines its tropism for CRFK cells
Author(s) :
Horzinek, M.C.
,
Verschoor, E.J.
,
Boven, L.A.
,
Blaak, H.
,
Vliet, A.L.W. van
,
Ronde, A. de
Description :
Feline immunodeficiency virus (FIV) isolates differ in the ability to replicate in Crandell feline kidney (CRFK) cells. The difference in tropism between two variants of the Dutch isolate FIV-UT113 was studied by using molecular clones which contained the envelope genes of the variants in a backgrou...
Repository :
Igitur Archive, Utrecht University repository
Language(s) :
English
Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease
Author(s) :
Visser, L.
,
Laman, J.D.
,
Heer, H.J. de
,
Boven, L.A.
,
Meurs, M. van
,
Melief, M.J.
,
Zahringer, U.
,
Strijp, J. van
,
Lambrecht, B.N.M.
Description :
Upon stimulation by microbial products through TLR, dendritic cells (DC) acquire the capacity to prime naive T cells and to initiate a proinflammatory immune response. Recently, we have shown that APC within the CNS of multiple sclerosis (MS) patients contain peptidoglycan (PGN), a major cell wall c...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Transfer of central nervous system autoantigens and presentation in secondary lymphoid organs
Author(s) :
Vos, A.F. de
,
Laman, J.D.
,
Meurs, M. van
,
Brok, H.P.M.
,
Boven, L.A.
,
Hintzen, R.Q.
,
Valk, P. van der
,
Ravid, R.
,
Rensing, S.
Description :
Dendritic cells are thought to regulate tolerance induction vs
immunization by transferring Ags and peripheral signals to draining lymph
nodes (LN). However, whether myelin Ag transfer and presentation in LN
occurs during demyelinating brain disease is unknown. In this study, we
...
Repository :
RePub (Erasmus University Repository)
Language(s) :
English
Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis
Author(s) :
Zwam, M. van
,
Huizinga, R.
,
Heijmans, N.
,
Meurs, M. van
,
Wierenga-Wolf, A.F.
,
Melief, M.J.
,
Hintzen, R.Q.
,
Hart, BA 't
Description :
Despite lack of classical lymphatic vessels in the central nervous system (CNS), cells and antigens do reach the CNS-draining lymph nodes. These lymph nodes are specialized to mediate mucosal immune tolerance, but can also generate T- and B-cell immunity. Their role in multiple sclerosis and experim...
Repository :
DSpace at Vrije Universiteit Amsterdam
Language(s) :
Undetermined
Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE
Author(s) :
Zwam, M. van
,
Huizinga, R.
,
Melief, M.J.
,
Wierenga-Wolf, A.F.
,
Meurs, M. van
,
Voerman, J.S.
,
Biber, K.P.H.
,
Boddeke, H.W.G.M.
Description :
Drainage of central nervous system (CNS) antigens to the brain-draining cervical lymph nodes (CLN) is likely crucial in the initiation and control of autoimmune responses during multiple sclerosis (MS). We demonstrate neuronal antigens within CLN of MS patients. In monkeys and mice with experimental...
Repository :
DSpace at Vrije Universiteit Amsterdam
Language(s) :
Undetermined
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Found 5 documents, displaying page 1 of 1