Results
author = "Bister, K"
Specific activation in jun-transformed avian fibroblasts of a gene (bkj) related to the avian beta-keratin gene family.
Description :
We have analyzed differential gene expression in normal versus jun-transformed avian fibroblasts by using subtracted nucleic acid probes and differential nucleic acid hybridization techniques for the isolation of cDNA clones. One clone corresponded to a gene that was strongly expressed in a previous...
Repository :
Europe PubMed Central
Language(s) :
English
Phosphorylation of specific sites in the gag-myc polyproteins encoded by MC29-type viruses correlates with their transforming ability.
Description :
The putative transforming proteins of the four acute leukaemia viruses belonging to the MC29 subgroup were shown to be phosphorylated in vivo. Comparison of the MC29 and CM11 encoded phosphoproteins revealed identical tryptic phosphopeptide maps, with both the gag and myc domains being phosphorylate...
Repository :
Europe PubMed Central
Language(s) :
English
Protein product of proto-oncogene c-mil.
Description :
Using antipeptide antibodies with specificity for the carboxyl termini of v-raf and v-mil protein products, two proteins with apparent molecular weights of approximately 71,000/73,000 and 215,000 were detected in immunoprecipitates from normal uninfected chicken cells. The 71,000/73,000-molecular-we...
Repository :
Europe PubMed Central
Language(s) :
English
Sequence-specific DNA binding by Myc proteins.
Description :
Myc proteins have a tripartite carboxyl-terminal domain containing specific amino acid sequence motifs: a basic motif, a helix-loop-helix motif, and a leucine heptad repeat. Similar sequence motifs have been identified in several eukaryotic transcription factors and were shown to facilitate protein-...
Repository :
Europe PubMed Central
Language(s) :
English
Avian oncovirus MH2: molecular cloning of proviral DNA and structural analysis of viral RNA and protein.
Description :
Viral RNA, molecularly cloned proviral DNA, and virus-specific protein of avian retrovirus MH2 were analyzed. The complexity and sequence conservation of the transformation-specific v-myc sequences of MH2 RNA were compared with those of the other members of the MC29 subgroup of acute leukemia viruse...
Repository :
Europe PubMed Central
Language(s) :
English
Structural relationship between a normal chicken DNA locus and the transforming gene of the avian acute leukemia virus MC29.
Description :
We screened a recombinant chicken DNA/lambda phage library for sequences homologous to the transformation-specific sequences of the avian acute leukemia virus MC29 by hybridization with molecularly cloned MC29 proviral DNA. Three cellular DNA clones were found and compared with each other and with t...
Repository :
Europe PubMed Central
Language(s) :
English
Phosphorylation of the nonstructural proteins encoded by three avian acute leukemia viruses and by avian fujinami sarcoma virus.
Description :
The gag gene-related, nonstructural proteins of three avian acute leukemia viruses (namely, myelocytomatosis viruses MC29 and CMII and avian erythroblastosis virus) and of avian Fujinami sarcoma virus (FSV) isolated by immunoprecipitation from cellular lysates with anti-gag serum were shown to be ph...
Repository :
Europe PubMed Central
Language(s) :
English
Two unrelated cell-derived sequences in the genome of avian leukemia and carcinoma inducing retrovirus MH2.
Description :
Molecularly cloned proviral DNA of avian replication-defective retrovirus Mill Hill No. 2 (MH2) was analyzed. The MH2 provirus measures 5.5 kb including two long terminal repeats (LTR), and contains a partial complement of the structural gene gag, 1.5 kb in size, near the 5' terminus, and a 1.3-kb s...
Repository :
Europe PubMed Central
Language(s) :
English
Molecular cloning of proviral DNA and structural analysis of the transduced myc oncogene of avian oncovirus CMII.
Description :
Molecularly cloned proviral DNA of avian oncogenic retrovirus CMII was isolated by screening a genomic library of a CMII-transformed quail cell line with a myc-specific probe. On a 10.4-kilobase EcoRI fragment, the cloned DNA contained 4.4 kilobases of CMII proviral sequences extending from the 5' l...
Repository :
Europe PubMed Central
Language(s) :
English
Oligoribonucleotide map and protein of CMII: detection of conserved and nonconserved genetic elements in avian acute leukemia viruses CMII, MC29, and MH2.
Description :
RNA and protein of the defective avian acute leukemia virus CMII, which causes myelocytomas in chickens, and of CMII-associated helper virus (CMIIAV) were investigated. The RNA of CMII measured 6 kilobases (kb) and that of CMIIAV measured 8.5 kb. By comparing more than 20 mapped oligonucleotides of ...
Repository :
Europe PubMed Central
Language(s) :
English