Managing severe infection in infancy in resource poor settings
Are diagnostic criteria for acute malnutrition affected by hydration status in hospitalized children? A repeated measures study
Abstract
Introduction
Dehydration and malnutrition commonly occur together among ill children in developing countries. Dehydration (change in total body water) is known to alter weight. Although muscle tissue has high water content, it is not known whether mid-upper arm circumferenc...
Effect of HIV infection on the acute antibody response to malaria antigens in children: an observational study
Are diagnostic criteria for acute malnutrition affected by hydration status in hospitalized children? A repeated measures study
Effect of HIV infection on the acute antibody response to malaria antigens in children: an observational study
Abstract
Background
In sub-Saharan Africa, the distributions of malaria and HIV widely overlap. Among pregnant and non-pregnant adults, HIV affects susceptibility to malaria, its clinical course and impairs antibody responses to malaria antigens. However, the relationship between th...
Age patterns of severe paediatric malaria and their relationship to Plasmodium falciparum transmission intensity
Abstract
Background
The understanding of the epidemiology of severe malaria in African children remains incomplete across the spectrum of
Mid-upper arm circumference at age of routine infant vaccination to identify infants at elevated risk of death: a retrospective cohort study in the Gambia
Neonatal seizures in a rural Kenyan District Hospital: aetiology, Incidence and outcome of hospitalization
Abstract
Background
Acute seizures are common among children admitted to hospitals in resource poor countries. However, there is little data on the burden, causes and outcome of neonatal seizures in sub-Saharan Africa. We determined the minimum incidence, aetiology and immediate out...
Congenital and neonatal malaria in a rural Kenyan district hospital: An eight-year analysis
Abstract
Background
Malaria remains a significant burden in sub-Saharan Africa. However, data on burden of congenital and neonatal malaria is scarce and contradictory, with some recent studies reporting a high burden. Using prospectively collected data on neonatal admissions to a ru...
Clinical indicators of bacterial meningitis among neonates and young infants in rural Kenya
Abstract
Background
Meningitis is notoriously difficult to diagnose in infancy because its clinical features are non-specific. World Health Organization (WHO) guidelines suggest several indicative signs, based on limited data. We aimed to identify indicators of bacterial meningitis ...