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author = "BRESOLIN, NEREO"
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Found 55 documents, displaying page 1 of 6

Effects of rituximab in two patients with dysferlin-deficient muscular dystrophy

Author(s) : Lerario Alberto , Cogiamanian Filippo , Marchesi Chiara , Belicchi Marzia , Bresolin Nereo , Porretti Laura , Torrente Yvan
Description :

Abstract

Background

The administration of rituximab (RTX) in vivo results in B-cell depletion, but evidence for multiple mechanisms of action have been reported. Surprisingly, B cell depletion produced a response in patients with polymyositis, which is characterized as a T ...

Repository : DOAJ-Articles
Language(s) : English

Both selective and neutral processes drive GC content evolution in the human genome

Author(s) : SIRONI, MANUELA , BRESOLIN, NEREO , COMI, GIACOMO PIETRO , CAGLIANI, RACHELE ANGELA
Description : Mammalian genomes consist of regions differing in GC content, referred to as isochores or GC-content domains. The scientific debate is still open as to whether such compositional heterogeneity is a selected or neutral trait. RESULTS: Here we analyze SNP allele frequencies, retrotransposon insertion ...
Repository : AIR - Archivio Istituzionale della Ricerca
Language(s) : English

Alpha1-antichymotrypsin induces TNF-alpha production and NF-kappaB activation in the murine N9 microglial cell line

Author(s) : SCARPINI, ELIO ANGELO , GALIMBERTI, DANIELA , BRESOLIN, NEREO , BRAGHIN, ELISA GAIA ALESSANDRA
Description :
Repository : AIR - Archivio Istituzionale della Ricerca
Language(s) : English

Heparan sulfate proteoglycan induces the production of NO and TNF-α by murine microglia

Author(s) : Bussini Simona , Meda Lucia , Scarpini Elio , Clementi Emilio , Conti Giancarlo , Tiriticco Marco , Bresolin Nereo , Baron Pierluigi
Description :

Abstract

Background

A common feature of Alzheimer's disease (AD) pathology is the abundance of activated microglia in neuritic plaques containing amyloid-beta protein (Aβ) and associated molecules including heparan sulfate proteoglycan (HSPG). Besides the role as pathological chaper...

Repository : DOAJ-Articles
Language(s) : English

The landscape of human genes involved in the immune response to parasitic worms

Author(s) : Fumagalli Matteo , Pozzoli Uberto , Cagliani Rachele , Comi Giacomo P , Bresolin Nereo , Clerici Mario , Sironi Manuela
Description :

Abstract

Background

More than 2 billion individuals worldwide suffer from helminth infections. The highest parasite burdens occur in children and helminth infection during pregnancy is a risk factor for preterm delivery and reduced birth weight. Therefore, helminth infections can be...

Repository : DOAJ-Articles
Language(s) : English

Comparative analysis of the human dystrophin and utrophin gene structures.

Author(s) : Pozzoli, Uberto , Sironi, Manuela , Cagliani, Rachele , Comi, Giacomo P , Bardoni, Alessandra , Bresolin, Nereo
Description : We present analysis of intronic sequences in the human DMD and UTRN genes. In both genes accumulation of repeated elements could account for intron expansion. Out-of-frame rod-domain exons have stronger splice sites and are separated by significantly longer introns as compared to in-frame exons. The...
Repository : Europe PubMed Central
Language(s) : English

Both selective and neutral processes drive GC content evolution in the human genome

Author(s) : Pozzoli Uberto , Menozzi Giorgia , Fumagalli Matteo , Cereda Matteo , Comi Giacomo P , Cagliani Rachele , Bresolin Nereo
Description :

Abstract

Background

Mammalian genomes consist of regions differing in GC content, referred to as isochores or GC-content domains. The scientific debate is still open as to whether such compositional heterogeneity is a selected or neutral trait.

Results

Here we analyze ...

Repository : DOAJ-Articles
Language(s) : English

A complex selection signature at the human AVPR1B gene

Author(s) : Cagliani Rachele , Fumagalli Matteo , Pozzoli Uberto , Riva Stefania , Cereda Matteo , Comi Giacomo P , Pattini Linda , Bresolin Nereo
Description :

Abstract

Background

The vasopressin receptor type 1b (AVPR1B) is mainly expressed by pituitary corticotropes and it mediates the stimulatory effects of AVP on ACTH release; common AVPR1B haplotypes have been involved in mood and anxiety disorders in humans, while r...

Repository : DOAJ-Articles
Language(s) : English

Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach

Author(s) : COMI, GIACOMO PIETRO , BRESOLIN, NEREO , CLERICI, MARIO SALVATORE , CAGLIANI, RACHELE ANGELA , SIRONI, MANUELA
Description : Viruses have exerted a constant and potent selective pressure on human genes throughout evolution. We utilized the marks left by selection on allele frequency to identify viral infection-associated allelic variants. Virus diversity (the number of different viruses in a geographic region) was used to...
Repository : AIR - Archivio Istituzionale della Ricerca
Language(s) : English

The landscape of human genes involved in the immune response to parasitic worms

Author(s) : CAGLIANI, RACHELE ANGELA , COMI, GIACOMO PIETRO , BRESOLIN, NEREO , SIRONI, MANUELA , CLERICI, MARIO SALVATORE
Description : BACKGROUND: More than 2 billion individuals worldwide suffer from helminth infections. The highest parasite burdens occur in children and helminth infection during pregnancy is a risk factor for preterm delivery and reduced birth weight. Therefore, helminth infections can be regarded as a strong sel...
Repository : AIR - Archivio Istituzionale della Ricerca
Language(s) : English
1 2 3 4 5 > >>

Found 55 documents, displaying page 1 of 6