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author = "BERRUTI, GIOVANNA"
1
Found 3 documents, displaying page 1 of 1
Acrosome biogenesis: Revisiting old questions to yield new insights
Description :
The acrosome is a unique membranous organelle located over the anterior part of the sperm nucleus that is highly conserved throughout evolution. This acidic vacuole contains a number of hydrolytic enzymes that, when secreted, help the sperm penetrate the egg's coats. Although acrosome biogenesis is ...
Repository :
Europe PubMed Central
Language(s) :
English
Failure of acrosome formation and globozoospermia in the wobbler mouse, a Vps54 spontaneous recessive mutant
Description :
The acrosome is a unique organelle that plays an important role at fertilization and during sperm morphogenesis and that is absent in globozoospermia, an inherited infertility syndrome in humans. At the light of recent experimental evidence, the acrosome is considered a lysosome-related organelle to...
Repository :
Europe PubMed Central
Language(s) :
English
Impaired Fertility and Spermiogenetic Disorders with Loss of Cell Adhesion in Male Mice Expressing an Interfering Rap1 Mutant
Author(s) :
Aivatiadou, Evanthia
,
Mattei, Elisabetta
,
Ceriani, Michela
,
Tilia, Leila
,
Berruti, Giovanna
Description :
The guanosine trisphosphatase Rap1 serves as a critical player in signal transduction, somatic cell proliferation and differentiation, and cell–cell adhesion by acting through distinct mechanisms. During mouse spermiogenesis, Rap1 is activated and forms a signaling complex with its effector, the ser...
Repository :
Europe PubMed Central
Language(s) :
English
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Found 3 documents, displaying page 1 of 1