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author = "Anderson, Frankie P."
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Found 7 documents, displaying page 1 of 1

The synthesis, structural characterization and biological evaluation of potential chemotherapeutic agents

Author(s) : Anderson, Frankie P.
Description : The design and synthesis of potent chemotherapeutics offers one of the most successful routes for the treatment of disease. A series of amino acid, dipeptidyl and stilbenyl derivatives have been synthesised and evaluated as potential therapeutic agents. These compounds were fully characterised by a ...
Repository : DORAS
Language(s) : English

2,3-Difluoro-N-(2-pyrid­yl)benzamide

Description : The title compound, C12H8F2N2O, crystallizes with two independent mol­ecules in the asymmetric unit. The independent mol­ecules differ slightly in conformation; the dihedral angles between the benzene and pyridine rings are 51.58 (5) and 49.97 (4)°. In the crystal structure, mol­ecules aggregate via...
Repository : Europe PubMed Central
Language(s) : English

2,3-Difluoro-N-(2-pyridyl)benzamide

Description : The title compound, C12H8F2N2O, crystallizes with two independent molecules in the asymmetric unit. The independent molecules differ slightly in conformation; the dihedral angles between the benzene and pyridine rings are 51.58 (5) and 49.97 (4)°. In the crystal structure, molecules aggregate via N-...
Repository : DORAS
Language(s) : English

A structural systematic study of four isomers of difluoro-N-(3-pyridyl)benzamide

Description : The four isomers 2,4-, (I), 2,5-, (II), 3,4-, (III), and 3,5-difluoro-N-(3-pyridyl)benzamide, (IV), all with formula C12H8F2N2O, display molecular similarity, with interplanar angles between the C6/C5N rings ranging from 2.94 (11)° in (IV) to 4.48 (18)° in (I), although the amide group is twisted fr...
Repository : DORAS
Language(s) : English

A structural systematic study of three isomers of difluoro-N-(4-pyridyl)benzamide

Description : The isomers 2,3-, (I), 2,4-, (II), and 2,5-difluoro-N-(4-pyridyl)benzamide, (III), all with formula C₁₂H₈F₂N₂O, all exhibit intramolecular C-H...O=C and N-H...F contacts [both with S(6) motifs]. In (I), intermolecular N-H...O=C interactions form one-dimensional chains along [010] [N...O = 3.0181 (16...
Repository : DORAS
Language(s) : English

Redetermination of para-aminopyridine (fampridine, EL-970) at 150 K

Description : The structure of fampridine (EL-970) or 4-aminopyridine, C₅H₆N₂, has been redetermined at 150 K. The room-temperature structure has been reported previously [Chao & Schempp (1977). Acta Cryst. B33, 1557-1564]. Pyramidalization at the amine N atom occurs in fampridine, with the N atom 0.133 (11) Å...
Repository : DORAS
Language(s) : English

Ethyl and isopropyl 4-ferrocenylbenzoate.

Description : The title compounds, [Fe(C5H5)(C14H13O2)] and [Fe(C5H5)- (C15H15O2)], respectively, contain the ferrocenyl 5(C5H4) and phenylene ±C6H4± rings in a nearly coplanar arrangement, with interplanar angles of 6.88 (12) and 10.5 (2), respectively. Molecules of the ethyl ester form dimers through 5(C5H5)CÐ ...
Repository : DORAS
Language(s) : English
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Found 7 documents, displaying page 1 of 1