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author = "Abolvardi, Sharareh S."
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RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2α
Author(s) :
van Hagen, Martijn
,
Overmeer, René M.
,
Abolvardi, Sharareh S.
,
Vertegaal, Alfred C. O.
Description :
Hypoxia-inducible factors (HIFs) are critical transcription factors that mediate cell survival during reduced oxygen conditions (hypoxia). At regular oxygen conditions (normoxia), HIF-1α and HIF-2α are continuously synthesized in cells and degraded via the ubiquitin–proteasome pathway. During hypoxi...
Repository :
Europe PubMed Central
Language(s) :
English
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Found 1 documents, displaying page 1 of 1