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Construction and characterization of a fully human antitumor immunoRNase selective for ErbB2-positive carcinomas: analysis of the role of the membrane transporter ABCC2/MRP2 in multidrug resistance (MDR)

Author(s) : Arciello, Angela
Description : The aim of the study was the construction and characterization of a novel, fully human immunoRNase (IR). IRs, chimeric proteins made up of a ribonuclease (RNase) molecule fused to an antibody moiety, represent a valid alternative to immunotoxins (ITs). ITs directed to cell surface molecular targets ...
Repository : fedOA , View repository documents
Language(s) : Undetermined
Subject(s) : MED/06 ONCOLOGIA MEDICA
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Publication Date(s) : 2005-01-01