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• (author = "Xu, LH")
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The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells

Author(s) : Song, LB , Li, J , Liao, WT , Feng, Y , Yu, CP , Hu, LJ , Kong, QL , Xu, LH , Zhang, X , Liu, WL , Li, MZ , Zhang, L , Kang, TB , Fu, LW , Huang, WL
Description : The polycomb group protein B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) is dysregulated in various cancers, and its upregulation strongly correlates with an invasive phenotype and poor prognosis in patients with nasopharyngeal carcinomas. However, the underlying mechanism of Bmi-1-mediated i...
Repository : The HKU Scholars Hub , View repository documents
Language(s) : English
Subject(s) : Nasopharynx - cytology - metabolism , Nuclear Proteins - antagonists and inhibitors - genetics - metabolism , PTEN Phosphohydrolase - genetics - metabolism , Proto-Oncogene Proteins - antagonists and inhibitors - genetics - metabolism , Repressor Proteins - antagonists and inhibitors - genetics - metabolism
Publisher(s) : American Society for Clinical Investigation. The Journal's web site is located at http://www.jci.org , United States
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Publication Date(s) : 2010-10-31