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Ammon's horn sclerosis: A maldevelopmental disorder associated with temporal lobe epilepsy

Author(s) : Blumcke, I , Thom, M , Wiestler, OD
Description : Ammon's horn sclerosis (AHS) is the major neuropathological substrate in patients with temporal lobe epilepsy (TLE). Histopathological hallmarks include segmental loss of pyramidal neurons, granule cell dispersion and reactive gliosis. Pathogenetic mechanisms underlying this distinct hippocampal pat...
Language(s) : Undetermined
Subject(s) : GRANULE CELL DISPERSION, HIPPOCAMPAL NEURON LOSS, CALRETININ-IMMUNOREACTIVE NEURONS, MAGNETIC-RESONANCE SPECTROSCOPY, FIBER SYNAPTIC REORGANIZATION, HUMAN DENTATE GYRUS, ADULT HUMAN BRAIN, WHITE-MATTER, CORTICAL DEVELOPMENT, HISTOPATHOLOGICAL FINDINGS
Publisher(s) : INT SOC NEUROPATHOLOGY
Contributor(s) :
Source(s) :
Publication Date(s) : 2002-04-01