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No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort study

Description : Background The transforming growth factor beta-1 gene (TGFB1) is a plausible candidate for breast cancer susceptibility. The L10P variant of TGFB1 is associated with higher circulating levels and secretion of TGF-beta, and recent large-scale studies suggest strongly that this variant is associated w...
Language(s) : Undetermined
Subject(s) : BRCA1, BRCA2, Risk modifiers, Hereditary cancer, TRANSFORMING-GROWTH-FACTOR-BETA-1 GENE, POLYMORPHISMS, BETA, SUSCEPTIBILITY, CONSORTIUM, TGF-BETA-1, VARIANT
Publisher(s) : SPRINGER
Contributor(s) :
Source(s) :
Publication Date(s) : 2009-05-01