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• (author = "Verbrugh, H.A.")
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Enhanced antifungal efficacy in experimental invasive pulmonary aspergillosis by combination of AmBisome with Fungizone as assessed by several parameters of antifungal response

Author(s) : Becker, M.J. , Marie, S. de , Fens, M.H. , Hop, W.C.J. , Verbrugh, H.A. , Bakker-Woudenberg, I.A.J.M.
Description : In common with a proportion of patients with invasive pulmonary aspergillosis (IPA), the efficacy of AmBisome treatment regimens in our rat model remains suboptimal. To investigate whether this might be the result of initially low antifungal activity of amphotericin B at the site ...
Repository : RePub (Erasmus University Repository) , View repository documents
Language(s) : English
Subject(s) : Animals , Female , Survival Analysis , Time Factors , Rats , Aspergillosis/*drug therapy , Biological Markers , Agranulocytosis/drug therapy/microbiology , Amphotericin B/adverse effects/*therapeutic use , Antibiotics, Antifungal/adverse effects/*therapeutic use , Aspergillosis, Allergic Bronchopulmonary/*drug therapy/microbiology/pathology , Chitin/metabolism , Drug Therapy, Combination/adverse effects/*therapeutic use , Lung/microbiology/pathology , Mannans/blood
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Publication Date(s) : 2002-01-01