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Histone variant macroH2A1 deletion in mice causes female-specific steatosis.

Description : BACKGROUND: Vertebrate heterochromatin contains a non-allelic variant of the histone H2A called macroH2A1, which has the characteristic of being three times the size of the canonical H2A. The macroH2A1 C-terminal extension can recruit onto chromatin the poly-ADP-ribose polymerase (PARP)1, which is c...
Language(s) : English
Subject(s) : [SDV:GEN] Life Sciences/Genetics
Publisher(s) :
Contributor(s) :
Source(s) : Epigenetics & Chromatin
Publication Date(s) : 2010-01-01