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• (author = "Sarasin, Alain")

Document details

Role of DNA polymerases eta, iota and zeta in UV resistance and UV-induced mutagenesis in a human cell line.

Author(s) : Gueranger, Quentin , Stary, Anne , Aoufouchi, Saïd , Faili, Ahmad , Sarasin, Alain , Reynaud, Claude-Agnès , Weill, Jean-Claude

Description : Genes coding for DNA polymerases eta, iota and zeta, or for both Pol eta and Pol iota have been inactivated by homologous recombination in the Burkitt's lymphoma BL2 cell line, thus providing for the first time the total suppression of these enzymes in a human context. The UV sensitivities and UV-in...

Repository : HAL - Hyper Article on Line , View repository documents

Language(s) : English

Subject(s) : [SDV:IMM] Life Sciences/Immunology , Burkitt's lymphoma cell line , translesion , UV damage , Rev3 , Cell cycle

Publisher(s) :

Contributor(s) :

Source(s) : DNA Repair

Publication Date(s) : 2008-09-01

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