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• (author = "Martinez, D.")
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Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production

Author(s) : Funes, JM , Quintero, M , Henderson, S , Martinez, D , Qureshi, U , Westwood, C , Clements, MO , Bourboulia, D , Pedley, RB , Moncada, S
Description : An increased dependency on glycolysis for ATP production is considered to be a hallmark of tumor cells. Whether this increase in glycolytic activity is due mainly to inherent metabolic alterations or to the hypoxic microenvironment remains controversial. Here we have transformed human adult mesenchy...
Repository : UCL Eprints , View repository documents
Language(s) : Undetermined
Subject(s) : adult stem cells, glycolysis, Warburg effect, HUMAN TUMOR-CELLS, CANCER-CELLS, AEROBIC GLYCOLYSIS, NUDE-MICE, METABOLISM, GROWTH, CARCINOGENESIS, MECHANISMS, APOPTOSIS, ELEMENTS
Publisher(s) : NATL ACAD SCIENCES
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Source(s) :
Publication Date(s) : 2007-04-10