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• (author = "Maréchal, V")
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Disappearance of lysosomal storage in spleen and liver of mucopolysaccharidosis VII mice after transplantation of genetically modified bone marrow cells.

Author(s) : Maréchal, V , Naffakh, N , Danos, O , Heard, JM
Description : Mice homozygous for the gusmps allele lack beta-glucuronidase activity and provide a useful model for human Mucopolysaccharidosis type VII (MPS VII), also known as Sly syndrome. Bone marrow (BM) transplantation was shown to correct the metabolic defect and to increase the life span of diseased anima...
Repository : UCL Eprints , View repository documents
Language(s) : English
Subject(s) : Animals, Bone Marrow Transplantation, Glucuronidase, Liver, Lysosomes, Mice, Mucopolysaccharidosis VII, Spleen, Transfection
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Publication Date(s) : 1993-08-15