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The delayed lung responses to single and repeated intratracheal administration of pure cobalt and hard metal powder in the rat.

Description : Epidemiological and clinical studies suggest that inhalation of cobalt metal dust (Co) mixed with tungsten carbide particles (WC), but not of cobalt dust alone, may cause interstitial pulmonary lesions (hard metal disease). In previous experimental studies in the rat, we have demonstrated the greate...
Language(s) : English
Subject(s) : Acetylglucosaminidase , Albumins , Animals , Arsenic Poisoning , Arsenicals , Bronchoalveolar Lavage Fluid , Cobalt , Disease Models, Animal , Female , Fibronectins , Hyaluronic Acid , L-Lactate Dehydrogenase , Lung , Oxides , Powders , Proteins , Pulmonary Fibrosis , Rats , Rats, Sprague-Dawley , Silicon Dioxide , Staining and Labeling , Trachea , Tungsten Compounds
Publisher(s) :
Contributor(s) : UCL
Source(s) :
Publication Date(s) : 1995-01-01