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Substance P protects spiral ganglion neurons from apoptosis via PKC-Ca2+-MAPK/ERK pathways

Description : In the current study, we have investigated the ability of substance P (SP) to protect 3-day-old (P3) rat spiral ganglion neurons (SGNs) from trophic factor deprivation (TFD)-induced cell death. The presence of SP high affinity neurokinin-1 receptor (NK1) transcripts was detected in the spiral gangli...
Language(s) : English
Subject(s) : apoptosis; neuroprotection; NK1; spiral ganglion neurons; substance P
Publisher(s) : BLACKWELL PUBLISHING LTD
Contributor(s) :
Source(s) :
Publication Date(s) : 2009-04-08