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• (author = "Jacobs, Koen")
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P-cadherin counteracts myosin II-B function : implications in melanoma progression

Author(s) : Jacobs, Koen , Van Gele, Mireille , Forsyth, Ramses , Brochez, Lieve , Vanhoecke, Barbara , De Wever, Olivier , Bracke, Marc
Description : BACKGROUND: Malignant transformation of melanocytes is frequently attended by a switch in cadherin expression profile as shown for E- and N-cadherin. For P-cadherin, downregulation in metastasizing melanoma has been demonstrated, and over-expression of P-cadherin in melanoma cell lines has been show...
Repository : Ghent University Repository , View repository documents
Language(s) : English
Subject(s) : Medicine and Health Sciences , RHO-FAMILY GTPASES , CULTURED-CELLS , BREAST-CANCER , EXPRESSION , INVASION , MIGRATION , PHOSPHORYLATION , LOCALIZATION , ACTIVATION , MORPHOLOGY
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Source(s) : MOLECULAR CANCER , ISSN: 1476-4598
Publication Date(s) : 2010-01-01