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Detection of the CCR5-Delta32 HIV resistance gene in Bronze Age skeletons.

Description : A mutant allele of the chemokine receptor CCR5 gene (CCR5-Delta32), which confers resistance to HIV-1 infection, is believed to have originated from a single mutation event in historic times, and rapidly expanded in Caucasian populations, owing to an unknown selective advantage. Among other candidat...
Language(s) : English
Subject(s) : European Continental Ancestry Group, Gene Frequency, Genetic Predisposition to Disease, Genetics, Population, HIV, HIV Infections, Humans, Plague, Receptors, CCR5, Selection, Genetic, Sequence Deletion
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Publication Date(s) : 2005-06-01