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Recruitment of Mad2 to the Kinetochore Requires the RodZw10 Complex

Author(s) : Dr Jun-yong Huang
Description : The spindle assembly or metaphase checkpoint is crucial to the proper segregation of chromosomes by the mitotic apparatus in all eukaryotes. The checkpoint mechanism in metazoans is more complex than that of yeast and requires additional proteins and activities besides the six classical Mads and Bub...
Language(s) : English
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Publication Date(s) : 2005-01-01