flag flag  

Glycogen synthase kinases 3α and 3β in cardiac myocytes: regulation and consequences of their inhibition

Description : Inhibition of glycogen synthase kinase 3β (GSK3β) as a consequence of its phosphorylation by protein kinase B/Akt (PKB/Akt) has been implicated in cardiac myocyte hypertrophy in response to endothelin-1 or phenylephrine. We examined the regulation of GSK3α (which we show to constitute a significant ...
Language(s) : Undetermined
Subject(s) :
Publisher(s) : Elsevier
Contributor(s) :
Source(s) :
Publication Date(s) : 2008-01-01