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Measurement and meaning of oxidatively modified DNA lesions in urine.

Description : BACKGROUND: Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide variety of diseases. The noninvasive assessment of such damage, i.e., in urine, and application to large-scale human studies are vital to understanding this role and devising intervention strategies. ME...
Language(s) : English
Subject(s) : Cell Death , DNA damage , DNA Repair , Deoxyguanosine , Diet , Enzyme-Linked Immunosorbent Assay , Oxidative Stress , Cell Death , DNA Damage , DNA Repair , Deoxyguanosine , Diet , Enzyme-Linked Immunosorbent Assay , Humans , Oxidative Stress
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Publication Date(s) : 2008-07-14