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Complexes between C1q and C3 or C4: novel and specific markers for classical complement pathway activation

Description : Classical pathway activation is often assessed by measuring circulating levels of activated C4. However, this parameter does not discriminate between activation through the classical or the lectin pathway. We hypothesized that during classical pathway activation, complexes are formed between C1q and...
Language(s) : Undetermined
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Source(s) : 298 , Journal of Immunological Methods , 35 , 45 , 1-2
Publication Date(s) : 2011-11-15