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• (author = "Bertolla, Carine")
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Synthesis and pharmacological evaluation of a new targeted drug carrier system: beta-cyclodextrin coupled to oxytocin.

Author(s) : Bertolla, Carine , Rolin, Stéphanie , Evrard, Brigitte , Pochet, Lionel , Masereel, Bernard
Description : Beta-cyclodextrin (beta-CD) was monofunctionalized into its carboxylic derivative and then conjugated to the N-side of oxytocin (OT), a nonapeptide involved in human behavior and myometrium contraction. On isolated rat myometrium, this conjugate (beta-CD-OT) partly preserves the contracting activity...
Repository : DIAL - Dépôt Institutionnel de l'Académie Louvain , View repository documents
Language(s) : English
Subject(s) : beta-Cyclodextrins , Uterine Contraction , Rats , Oxytocin , Oxytocics , Myometrium , Molecular Structure , Magnetic Resonance Spectroscopy , Female , Drug Carriers , Chromatography, High Pressure Liquid , Animals
Publisher(s) :
Contributor(s) : FUNDP
Source(s) :
Publication Date(s) : 2008-01-01